… gut-derived peptides, including glucagon-like peptide-1 (GLP-… Therefore, the central regulation
of energy balance is a key … in the brain along with the blood-brain barrier. GLP-1 reached …

… Post hoc tests determined the simple main effects if the … -2 to cross the blood-brain barrier
and activate its receptors on … hormone transport across the blood-brain barrier 38 have been …

… The blood-brain barrier (BBB), a dynamic interface between blood and brain constituted … a
central role in the assembly and organization of claudins, occludin, and JAMs, and links these …

… , blood-brain barrier (BBB) breakdown, and an imbalance in neurotransmitter secretion in
the central … Therefore, many researchers have investigated the relationship between diabetic …

… the many T2DM-associated complications, damage to the central and peripheral nervous …
Glucose transport across the blood–brain barrier (BBB) is tightly regulated by the glucose …

… DA-CH5 is a novel GLP-1/GIP receptor unimolecular co-agonist with a novel peptide
sequence added to cross the blood-brain barrier. Here we showed that both exendin-4 and DA-…

… of the vagus nerve and glucagon like peptide-1 in appetite … The connections among the
central nervous system (CNS), … is expressed in the PNS, blood brain barrier, the colon, immune …

… a therapeutic potential in central nervous system diseases. … could enter the brain through
the blood brain barrier (BBB) [9], … could exert multiple effects on the central nervous system (…

… However, there is strong evidence that central and peripheral immune responses undergo
… Developing a GLP-1RA that crosses the blood-brain barrier and targets brain areas affected …

… and later enter the CNS to elicit central activities. Others, like … studies alleviated blood-brain
barrier leakage has been … Ex-4 pretreatment was alleviated blood-brain barrier leakage …