… and metabolic consequences of glucagon-like peptide 1 (… are located behind the blood–brain
barrier, shielded from the … benefit do not cross the blood–brain barrier, yet they manage …

… one of the links for peripheral GLP-1 action to activate central … the blood-brain barrier (BBB)
could have relevant effects on … have close neuroanatomical connections with hypothalamic …

… In addition, glucagon like peptide-1 receptor agonists (GLP-… and therapeutic effects of
GLP-1RAs on the central nervous … lixisenatide can penetrate the blood-brain barrier, liraglutide …

… the blood–brain barrier (BBB) to activate receptors on neurons (Hunter and Holscher, 2012)
and exert beneficial effects to … The main pathological findings of PD are profound loss of …

… are distributed throughout the central nervous system. GLP-1 … of cerebral blood flow and
blood-brain barrier function – it is involved … Blood–brain barrier integrity has also been shown to …

… produced by the gut may cross the blood–brain barrier and may reach the hypothalamic
arcuate … A schematic representation of the main effects of the hormone in the digestive system is …

… peptides participate in this axis, glucagon-like peptide-1 (GLP-1) plays a central role. GLP-1 …
through the blood–brain barrier and penetration into deeper brain regions differ between the …

… Here, we find that sympathetic nerves elevate postprandial blood glucose but restrict
brain glucose utilization by repressing the release of glucagon-like peptide-1 (GLP-1) from …

… the central nervous system ( 7). GLP-1 analogues, classically used for the treatment of diabetes
are able to cross the blood-brain barrier … versus central effects of glucagon-like peptide-1 …

… This led Kastin to propose that peptides could cross the blood-brain barrier (BBB). Although
initially very controversial, Kastin, I, and others demonstrated not only that peptides can …