Protein acetylation and deacetylation: An important regulatory modification in gene transcription

C Xia, Y Tao, M Li, T Che, J Qu - Experimental and …, 2020 - spandidos-publications.com
… The research history of protein acetylation has spanned >50 years. Lysine … and
lysosome-related gene expression, can be acetylated by GCN5 at K274 and K279 in the way of Nε-…

Modulation of cellular processes by histone and non-histone protein acetylation

M Shvedunova, A Akhtar - Nature reviews Molecular cell biology, 2022 - nature.com
… Histone acetylation and non-histone protein acetylation influence a myriad of … We begin
by describing the influence of histone acetylation on … Gene regulation by histone acetylation

Acetate revisited: A key biomolecule at the nexus of metabolism, epigenetics and oncogenesis—Part 1: Acetyl-CoA, acetogenesis and acyl-CoA short-chain …

JR Moffett, N Puthillathu, R Vengilote… - Frontiers in …, 2020 - frontiersin.org
… cellular regulatory molecule with diverse functions beyond the … , which links mitochondrial
metabolism to a wide array of … to enzyme and gene regulation through protein acetylation. It …

Who rules the cell? An epi-tale of histone, DNA, RNA, and the metabolic deep state

J Leung, V Gaudin - Frontiers in Plant Science, 2020 - frontiersin.org
… with a global 50%–70% increase in histone acetylation over … on the epigenetic regulation
of gene expression. … Most of these newer adducts in Figure 1 are beyond the remit …

Acetate revisited: a key biomolecule at the nexus of metabolism, epigenetics, and oncogenesis–part 2: acetate and ACSS2 in health and disease

JR Moffett, N Puthillathu, R Vengilote… - Frontiers in …, 2020 - frontiersin.org
… targeted protein acetylation reactions that can regulate central … plays in transcriptional
regulation and cancer metabolism. … of 9 years of follow-up of a large group of people aged 50–71, …

The evolving metabolic landscape of chromatin biology and epigenetics

Z Dai, V Ramesh, JW Locasale - Nature Reviews Genetics, 2020 - nature.com
… we refer to as epigenetic modifications, together form the epigenome and are linked to gene
regulation and thus to … Each modification is derived from intermediates from metabolism. …

The role of protein acetylation in carcinogenesis and targeted drug discovery

J Yang, C Song, X Zhan - Frontiers in Endocrinology, 2022 - frontiersin.org
… This article discussed the roles of protein acetylation in tumor pathology and therapeutic …
50 years of protein acetylation: from gene regulation to epigenetics, metabolism and beyond. …

Advances in nutritional epigenetics—A fresh perspective for an old idea. Lessons learned, limitations, and future directions

L Sedley - Epigenetics Insights, 2020 - journals.sagepub.com
epigenetic mechanisms is the regulation of gene expression, … acetyl group for histone and
protein acetylation. ATP is used … serotonylation to influence gene expression beyond the BBB…

Histone acylation at a glance

S Bhattacharya, BP Tu - Journal of Cell Science, 2024 - journals.biologists.com
… of gene expression regulation is the epigenetic modification of … Beyond acetylation, there is
evidence now that histones can … for protein acylation, which means that metabolic disorders …

Protein acetylation: a novel modus of obesity regulation

Y Liu, H Yang, X Liu, H Gu, Y Li, C Sun - Journal of Molecular Medicine, 2021 - Springer
… energy metabolism [6]. Therefore, this review will focus on the role of protein acetylation in …
Meanwhile, acetylation regulates gene expression by modifying histones and non-histones; it …