… on [4Fe-4S] clusters for its essential cellular function and … nucleotide binding, while the Nbp35
subunit plays a crucial … of Cfd1-Nbp35 proteins in the Fe single bond S cluster biogenesis …

… is necessary for CIA function, but the role of nucleotide hydrolysis … cerevisiae, exploit nucleotide
binding and hydrolysis to … -Cfd1 heterodimer, which binds two [4Fe-4S] clusters. Stir the …

… body formed by two nucleotide binding domains (NBS) … , the 4Fe-4S cluster is assembled on
a Cfd1-Nbp35 heterodimer … groups — labile 4Fe-4S clusters (or bridging clusters) which are …

… The nucleotide binding site is a pocket with positive charges, … To explore how ApbC binds
to the [4Fe-4S] cluster potentially… a [4Fe-4S] cluster binds to two Cfd1 protomers and is bridged …

… essential for the maturation of cytosolic [4Fe–4S] proteins. We show here that dimeric
cluster-bridged GLRX3 transfers its [2Fe–2S] 2+ clusters … , and in the Cfd1–Nbp35 heterocomplex. (…

… that play important roles in respiration, … -bridging a [4Fe-4S] cluster at the surface of the
homodimer was confirmed [39]. The Cfd1 Ct -dimeric architecture of the nucleotide binding …

… heterodimeric complexes, through a bridging [4Fe-4S] cluster bound to a CxxC motif …
essential for yeast cell viability and for cytosolic [4Fe-4S] proteins activity.However, this functional …

… cluster binding to yeast Cfd1-Nbp35 does not require cGrxs, making a cluster-trafficking
function of cGrxs to Cfd1-Nbp35 … is not essential for a critical flow of [4Fe-4S] clusters via the CIA …

… by two homologous P-loop nucleoside triphosphatases (NTPases) … 4Fe−4S] cluster bridging
two protein molecules in homodimeric Nbp35, in homodimeric Cfd1, and in the Cfd1−Nbp35 …

… assembled 4Fe–4S cluster from the CFD1-NBP35 scaffold … Helicase XPD is an important
bridge between these two … that XPD coordinates a 4Fe–4S cluster, which is a key determinant of …