[HTML][HTML] Adiponectin: a promising target for the treatment of diabetes and its complications

M Begum, M Choubey, MB Tirumalasetty, S Arbee… - Life, 2023 - mdpi.com
adiponectin impacts critical pathways implicated in diabetic nephropathy, retinopathy, neuropathy,
… In addition, we explore possible treatment options for increasing adiponectin levels or …

[HTML][HTML] Identification of a novel adiponectin receptor and opioid receptor dual acting agonist as a potential treatment for diabetic neuropathy

OKF Ma, S Ronsisvalle, L Basile, AW Xiang… - Biomedicine & …, 2023 - Elsevier
… emerged as good ligands to adiponectin receptors showing some 2D and … adiponectin
receptors that may have analgesic effects and neuroprotective effects to treat diabetic neuropathy

[HTML][HTML] Adiponectin in chronic kidney disease

J Przybyciński, V Dziedziejko, K Puchałowicz… - International journal of …, 2020 - mdpi.com
… There is also a significant growth of serum adiponectin levels in diabetic nephropathy, …
of diabetic nephropathy. This chiefly contributes to elevation of the HMW form of adiponectin, …

[HTML][HTML] Adiponectin in renal fibrosis

H Jing, S Tang, S Lin, M Liao, H Chen, Y Fan… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
… Studies have reported that AdipoRon may be a promising agent to treat diabetic nephropathy
by stimulating intracellular calcium ions, activating the AMPK-LKB1/PPARα signaling …

… , urinary adiponectin, urinary Retinol Binding Protein, and serum zinc alpha 2 glycoprotein levels as novel biomarkers for early diagnosis of diabetic nephropathy: a …

MF Kamel, M Nassar, A Elbendary… - Diabetes & Metabolic …, 2022 - Elsevier
… ZAG is excreted in the urine of diabetics with microalbuminuria [29]. This study aims to
investigate the potential use of urinary transferrin, adiponectin, RBP, and serum ZAG levels as …

Adiponectin promotes repair of renal tubular epithelial cells by regulating mitochondrial biogenesis and function

Y Chen, Y Yang, Z Liu, L He - Metabolism, 2022 - Elsevier
… Mitochondrial biogenesis and dysfunction are associated with renal tubular epithelial cell
injury and the pathophysiological development of diabetic nephropathy (DN). Adiponectin (…

[HTML][HTML] Adiponectin protects obesity-related glomerulopathy by inhibiting ROS/NF-κB/NLRP3 inflammation pathway

X Xu, X Huang, L Zhang, X Huang, Z Qin, F Hua - BMC nephrology, 2021 - Springer
… To ascertain the protective effect of adiponectin on PA-treated podocytes, we transfected
MPC5 cells with siRNA against adiponectin. The transfection efficiency was evaluated by qRT-…

[HTML][HTML] High serum adiponectin as a biomarker of renal dysfunction: Results from the KNOW-CKD study

SH Song, TR Oh, HS Choi, CS Kim, SK Ma, KH Oh… - Scientific reports, 2020 - nature.com
… between serum adiponectin levels and … Adiponectin is associated with early diabetic
kidney disease in adults with type 1 diabetes: A Coronary Artery Calcification in Type 1 Diabetes

[HTML][HTML] Adiponectin gene polymorphisms associated with diabetes mellitus: A descriptive review

M Howlader, MI Sultana, F Akter, MM Hossain - Heliyon, 2021 - cell.com
… of adiponectin in ob/ob mice and treatment of obese diabetic or lipoatrophic mice with
adiponectin … and uncoupling protein 2, which suggest that adiponectin might activate PPAR-α [ …

Serum Adiponectin as a Diagnostic Marker of Nephropathy among Patients with Type 2 Diabetes Mellitus: A Cross-sectional Study.

G VELURI, M MURUGAN, SP PALEM… - Journal of Clinical & …, 2022 - search.ebscohost.com
… The ROC curves were constructed to investigate the diagnostic accuracy of identifying
markers of diabetic nephropathy in T2DM patients with normoalbuminuria compared to controls. …