… those studies focussed on agrin and may reflect decreases in … led to early cerebral
microvascular degeneration, BBB … the CSF level of a cleaved, soluble form of platelet-derived …

… microvascular media tunica damage but also microvascular … of agrin in AD cases. Preclinical
studies have suggested that … Agrin in Alzheimer's disease: altered solubility and abnormal …

… methods such as laser capture microdissection (LCM) would include everything within the
specified area. The problems can, to some extent, be overcome by appropriate controls, eg …

… (C) Soluble Aβ is drained via the perivascular route along … microvascular RAGE
immunoreactivity in the hippocampus. It is not surprising then, that the upregulation of RAGE can …

… on the potential effects of abnormal HS expression on Aβ … (SULF) genes was altered in
human AD brains, with the … Increased soluble agrin with higher Braak stage diagnoses (…

… on the potential effects of abnormal HS expression on Aβ … (SULF) genes was altered in
human AD brains, with the … Increased soluble agrin with higher Braak stage diagnoses (…

… HSPGs), such as perlecan and agrin. Laminin and col IV are the … Fibronectin is a large
glycoprotein that exists in a soluble … MV is not appreciably altered following development of ADNC …

… (5) altered laminin and agrin distribution may impair AQP4 … pathway, abnormal focal deposits
of agrin and laminin could … in part, by altering the perivascular transport of soluble Aβ 1 – …

… It is mainly composed of brain microvascular endothelial cells … Similarly, controversial findings
exist on how agrin is altered … , agrin in normal brains is soluble in 1%SDS, while agrin from …

… Specialized microvascular endothelial cells with a basal … cells, and the fibronectin, agrin,
and laminins-containing astroglial … approaches to estimate solubility and permeability in drug …