Importance Data on the use of antiretroviral drugs, including new drugs and formulations, for
the treatment and prevention of HIV infection continue to guide optimal practices. Objective
To evaluate new data and incorporate them into current recommendations for initiating HIV
therapy, monitoring individuals starting on therapy, changing regimens, preventing HIV
infection for those at risk, and special considerations for older people with HIV. Evidence
Review New evidence was collected since the previous International Antiviral (formerly …

Importance Recent advances in treatment and prevention of HIV warrant updated
recommendations to guide optimal practice. Objective Based on a critical evaluation of new
data, to provide clinicians with recommendations on use of antiretroviral drugs for the
treatment and prevention of HIV, laboratory monitoring, care of people aging with HIV,
substance use disorder and HIV, and new challenges in people with HIV, including COVID-
19 and monkeypox virus infection. Evidence Review A panel of volunteer expert physician …