Trends and strategies to combat viral infections: A review on FDA approved antiviral drugs

DR Tompa, A Immanuel, S Srikanth… - International journal of …, 2021 - Elsevier
… molecules have different mechanisms of antiviral activity and based on their structure and/or …
all the antiviral agents that are developed since the approval of first drug molecule by FDA …

A decade of FDA-approved drugs (2010–2019): trends and future directions

DG Brown, HJ Wobst - Journal of medicinal chemistry, 2021 - ACS Publications
… By far the largest impact in antiviral drug discovery in the past decade was in hepatitis C …
on year of approval (Figure 16). We found that on average 37% of new drugs over the past

A review: Mechanism of action of antiviral drugs

S Kausar, F Said Khan… - International journal …, 2021 - journals.sagepub.com
antiviral drugs are getting approved for the use of human either due to the side effects or
resistance to antiviral drugs… for antiviral will speed up the novel antiviral drugs development. The …

FDA approved drugs with pharmacotherapeutic potential for SARS-CoV-2 (COVID-19) therapy

S Drożdżal, J Rosik, K Lechowicz, F Machaj… - Drug resistance …, 2020 - Elsevier
… In addition to the drugs discussed in the current review, many antiviral drugs have been
explored for COVID-19 treatment for several months, without any positive effect. Neuraminidase …

… -2: recent reports on antiviral therapies based on lopinavir/ritonavir, darunavir/umifenovir, hydroxychloroquine, remdesivir, favipiravir and other drugs for the treatment …

M Costanzo, MAR De Giglio… - Current medicinal …, 2020 - ingentaconnect.com
approved antiviral treatment for the new virus is available. Therefore, identifying drugs with
antiviral … and, to this aim, testing already existing antiviral drugs against SARS-CoV-2 is an …

US FDA approved drugs from 2015–June 2020: a perspective

P Bhutani, G Joshi, N Raja, N Bachhav… - Journal of Medicinal …, 2021 - ACS Publications
… 245 drugs, including small and macromolecules approved by … Nearly 29% of the drugs
were approved for the treatment of … of the approved drugs according to the year of approval, …

[HTML][HTML] Repurposed antiviral drugs for Covid-19—interim WHO solidarity trial results

WHO Solidarity Trial Consortium - … England journal of medicine, 2021 - Mass Medical Soc
… other WHO expert groups identified four repurposed antiviral drugs that might have at least
a … protocol approved by the WHO ethics review committee and local protocols approved by …

[HTML][HTML] Current status of oral antiviral drug treatments for SARS-CoV-2 infection in non-hospitalized patients

DV Parums - … science monitor: international medical journal of …, 2022 - ncbi.nlm.nih.gov
… trial, treatment with molnupiravir began within 72 hours after the onset of symptoms in 50% …
There are some early lessons from this initial approval of an oral antiviral drug to treat SARS…

[HTML][HTML] Discovery and development of safe-in-man broad-spectrum antiviral agents

PI Andersen, A Ianevski, H Lysvand… - International Journal of …, 2020 - Elsevier
After approval and marketing of the drug, phase IV may be initiated to follow up on … approved
against FLUAV in Japan; cidofovir is an injectable antiviral medication used as a treatment

[HTML][HTML] Remdesivir: first approval

YN Lamb - Drugs, 2020 - Springer
… conditional approval for the treatment of COVID-19. … during June and July 2020, remdesivir
was approved as an emergency medication in the UAE [19] and received restricted approval