GCH1 variants contribute to the risk and earlier age-at-onset of Parkinson's disease: a two-cohort case-control study

H Pan, Y Zhao, J Mei, Z Fang, Y Wang, X Zhou… - Translational …, 2020 - Springer
association test. We also performed a meta-analysis to correlate deleterious GCH1 variants
with … Apart from the earlier reported variants, we also found several novel missense or loss-of-…

Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction

DV Conti, BF Darst, LC Moss, EJ Saunders, X Sheng… - Nature …, 2021 - nature.com
… disease with large disparities in … meta-analysis of prostate cancer genome-wide association
studies (107,247 cases and 127,006 controls) and identified 86 new genetic risk variants

Cross-ancestry genome-wide meta-analysis of 61,047 cases and 947,237 controls identifies new susceptibility loci contributing to lung cancer

J Byun, Y Han, Y Li, J Xia, E Long, J Choi, X Xiao… - Nature …, 2022 - nature.com
… 10 new lead associations from previously reported loci. Rare-… top association signals in
multiancestry casecontrol meta-… an overlap between GWAS variants (variants that are linked …

Systematic review and meta-analysis of genetic association studies of pelvic organ prolapse

K Allen-Brady, JWF Chua, R Cuffolo, M Koch… - International …, 2022 - Springer
… We pre-specified inclusion of both case-control and cross-… equivalent for meta-analysis
purposes; results are reported based … identified four variants through meta-analysis of candidate …

Association of eNOS and MCP-1 Genetic Variants with Type 2 Diabetes and Diabetic Nephropathy Susceptibility: A CaseControl and Meta-Analysis Study

P Raina, R Sikka, H Gupta, K Matharoo, SK Bali… - Biochemical …, 2021 - Springer
previous studies have reported a positive association of … variants on the different covariates
presented previously (Raina et al. 2015b) and in this paper. Among all the variants tested in …

[HTML][HTML] Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline

M Gorski, B Jung, Y Li, PR Matias-Garcia, M Wuttke… - Kidney international, 2021 - Elsevier
reported for increased ESKD risk. Our work is unique in its large sample size for these 2
case-control … sample size, we cannot exclude that the lack of association of an identified variant

Genome-wide association meta-analysis of spontaneous coronary artery dissection identifies risk variants and genes related to artery integrity and tissue-mediated …

D Adlam, TE Berrandou, A Georges, CP Nelson… - Nature Genetics, 2023 - nature.com
… , and confirm the previously reported associations near ADAMTSL4 … imputed variants in one
of the individual casecontrol studies, we … We also performed Cochran’s Q test to assess the …

The association between ATM variants and risk of breast cancer: a systematic review and meta-analysis

M Moslemi, Y Moradi, H Dehghanbanadaki, H Afkhami… - BMC cancer, 2021 - Springer
… In this study, w Cochran’s Q test and I square statistic was used to … in the current meta-analysis
are reported in Tables 1 and 2. … The meta-analysis on the adjusted case-control studies …

Large-scale rare variant burden testing in Parkinson's disease

MB Makarious, J Lake, V Pitz, A Ye Fu, JL Guidubaldi… - Brain, 2023 - academic.oup.com
… We identify potential novel risk associations for variants in … In summary, the two meta-analysis
approaches used in this … Biobank case-control dataset; and (ii) a meta-analysis of the …

DNA methylation meta-analysis reveals cellular alterations in psychosis and markers of treatment-resistant schizophrenia

…, Wellcome Trust Case Control Consortium (WTCCC)… - Elife, 2021 - elifesciences.org
… We implemented a stringent pipeline to meta-analyze epigenome-wide association study
(… of colocalization to regions nominated by genetic association studies of disease. Many …