… Deguelin activates the Rb by activating the phosphorylation … Furthermore, apoptosis-inducing
the ability of Deguelin has … The increased expression of BAD implies that BAD escape phos…

… both been shown to decrease apoptosis. The PI3K/AKT pathway plays a critical role in
the phosphorylation of Bcl-2 and BAD resulting in decreased overall apoptosis. The ERK/P90RSK …

… We did not detect any significant changes in phosphorylation of protein kinase B (Akt), … the
proapoptotic protein BAD via p90RSK [56], which causes loss of the inhibitory effect of BAD on …

… any significant changes in phosphorylation of protein kinase B (… of other proteins that also
can prevent apoptosis by inhibiting … BAD is inhibited by phosphorylation at serine (Ser) 112 by …

… phosphorylation state of Rb protein, altering the role of Rb … Activation of CDK1 plays a
significant role in apoptosis … correlation between high CDK7 levels and poor prognosis [53]. …

… CDK1 was found to be highly upregulated across several malignancies and is associated
with poor overall and relapse-free survival. Molecular docking and dynamics evaluation …

… A functional protein microarray is another type of protein microarray that allows the study
of … of proteins such as protein-DNA, protein-RNA, protein–protein, protein-ligand, protein-drug, …

… selection of variants of tumor cell that escapes the immune response by various mechanisms
… cells that allow explicit escape from immune response and tumor progression [9, 10] Fig. 1. …

… The phosphorylation of specific residues is critical for the cellular functioning of proteins such
as … Therefore, dysregulation in the phosphorylation of the protein is considered to be a valid …

… poor association between mRNA (messenger ribonucleic acid) at large and the corresponding
protein … expression of six proteins associated with cell cycle progression, apoptosis, and …