Current approaches in computational psychiatry for the data-driven identification of brain-based subtypes

LR Brucar, E Feczko, DA Fair, A Zilverstand - Biological psychiatry, 2023 - Elsevier
… These methods have been applied to psychiatric populations … In their simplest form, these
approaches stratify populations by … of split-sample methods or a single subsample split of the …

Cross-disorder Genetics in Neuropsychiatry

E Van Assche, EC Schulte, OA Andreassen… - Frontiers in …, 2022 - frontiersin.org
… (“splitting”), whereas others believe in continua without clear boundaries (“lumping”). This
focus on the similarities and the differences between neurology and psychiatry illustrates the …

Advances in the computational understanding of mental illness

QJM Huys, M Browning, MP Paulus… - …, 2021 - nature.com
… -driven computational approaches to psychiatric illness are … review as here it will not be
possible to review all the work. … of these approaches are beyond the scope of this review, and …

A review of approaches and models in psychopathology conceptualization research

NR Eaton, LF Bringmann, T Elmer, EI Fried… - Nature Reviews …, 2023 - nature.com
mental disorders at the intersection of the three approaches. … In a separate line of inquiry,
analyses of common mental … Theory building and testing are required to move beyond the …

Mathematical nosology: computational approaches to understanding psychosis

AR Powers - Schizophrenia Research, 2022 - Elsevier
… of computational methods as applied to psychiatric illness. In … translate directly to risk
stratification and treatment response … of theory-based approaches extends well beyond their direct …

The normative modeling framework for computational psychiatry

S Rutherford, SM Kia, T Wolfers, C Fraza, M Zabihi… - Nature protocols, 2022 - nature.com
… developed to provide additional information beyond what can be learned from case–control
modeling approaches (see ‘… Therefore, we stratify the train–test split using the site variable. …

Functional MRI applications for psychiatric disease subtyping: a review

L Miranda, R Paul, B Pütz, B Müller-Myhsok - arXiv preprint arXiv …, 2020 - arxiv.org
… They used this approach to cluster a sample of 134 subjects including both patients and
controls and selected the ​view with the greatest Cohen's D coefficient when separating cases …

[PDF][PDF] Embracing variability in the search for biological mechanisms of psychiatric illness

A Segal, J Tiego, L Parkes, AJ Holmes, AF Marquand… - osf.io
… knowledge of mental diseases is an accurate definition of the separate disease processes.
… Evidence for selective, disorder-specific targeting of neural systems beyond such …

[HTML][HTML] The promise of a model-based psychiatry: building computational models of mental ill health

TU Hauser, V Skvortsova, M De Choudhury… - The Lancet Digital …, 2022 - thelancet.com
review the different computational approaches and their respective data sources that have
been used in academic research. Rather than present a systematic literature review, … to split

Systematic review of functional MRI applications for psychiatric disease subtyping

L Miranda, R Paul, B Pütz, N Koutsouleris… - … in Psychiatry, 2021 - frontiersin.org
approaches in their study, here we will only discuss their unsupervised clustering, which
implicated two separate … further data-driven stratification of psychiatric diseases can help dissect …