… , which modulates human Th17 responsiveness by altering the biological activity of acid …
T Helper 17 cells play a critical pathogenic role in lung cancer. Proc Natl Acad Sci USA (…

… + T helper (Th) cells differentiate into distinct Th effector cell … metabolism, to control human
Th17 cell plasticity. We discuss the … to better understand Th17 biology in order to manipulate it …

… T helper type 17 (Th17) cells are characterized by inherent plasticity and heterogeneity …
aforementioned studies highlight lipid metabolism as a vital component of Th17 cell biology. …

… Growing evidence regarding the biology of IL-10 in T cells suggests that Th1 and Th17 cells
self-limit … among polarized T helper cells highlighted the significance of Th cell plasticity and …

… T helper (Th) cells, especially Th17 cells. While various preclinical and clinical studies
have reported increased levels of Th17 cells … The plasticity exhibited by Th17 cells is well-known …

… In addition to the classical T helper cells, ie, Th1 and Th2, several … significant steps are
required for CD4 T cell plasticity. First, extracellular signals initiate the process of polarising cells …

… plasticity. Of note, there have been phenotypical transitions reported between Th17 cells
and all other T helper … on different T helper subsets and their functions in cancer biology, it is …

… T helper cells was published by Mosmann and Coffmann in 1986 (Mosmann et al. 1986).
They have identified two types of T helper cells (Th cells… involvement in Tr1 cell biology. These …

… Ampka1-deficient T cells show reduced metabolic plasticity and mitochondrial bioenergetic
when glucose is limited (84). Under glucose-limiting conditions, reduced expression of IFN-γ …

… However, recent studies demonstrate the importance of T cell plasticity and polyfunctionality
in infection and autoimmunity 8, 13, 14. Elevated T cell proinflammatory cytokine responses …