Leveraging the biology of adversity and resilience to transform pediatric practice

JP Shonkoff, WT Boyce, P Levitt, FD Martinez… - …, 2021 - publications.aap.org
stress during sensitive periods in development can all predispose to inflammatory airway …
racism, and other deeply embedded structural inequities impose on families raising young …

Adverse childhood experiences and severity levels of inflammation and depression from childhood to young adulthood: a longitudinal cohort study

E Iob, R Lacey, V Giunchiglia, A Steptoe - Molecular psychiatry, 2022 - nature.com
inflammation as a mediating mechanism through which ACEs may become biologically
embedded … in understanding stress-related inflammatory responses in children and adolescents […

[HTML][HTML] Adverse childhood experiences and early life inflammation in the Avon longitudinal study of parents and children

RE Lacey, M Bartley, M Kelly-Irving… - …, 2020 - Elsevier
… three methods of ACE operationalisations and inflammatory … However the number of
stresses included was very diverse … as to how these biological processes might operate and in …

The prospective association between stressful life events and inflammation among adolescents with a history of early institutional rearing

A Tang, M Wade, NA Fox, CA Nelson… - Development and …, 2020 - cambridge.org
biological embedding model which accounts for early stress … Identifying social and biological
processes, such as stressful … with levels of inflammation in a cohort of children with similar …

Immune and epigenetic pathways linking childhood adversity and health across the lifespan

MA Chen, AS LeRoy, M Majd, JY Chen… - Frontiers in …, 2021 - frontiersin.org
… For example, biological embedding models of childhood … life stress increases the risk of
elevated inflammation through … that the effect of childhood adversity on inflammation among …

Challenges in researching the immune pathways between early life adversity and psychopathology

B Reid, A Danese - Development and psychopathology, 2020 - cambridge.org
… the inflammatory outcomes arising from childhood adversity … between early life stress and
increased inflammation. Evidence … , the processes by which ELA may instantiate inflammation

[HTML][HTML] Exposure to adversity and inflammatory outcomes in mid and late childhood

M O'Connor, AL Ponsonby, F Collier, R Liu… - Brain, Behavior, & …, 2020 - Elsevier
… Chronically activated stress responses may result in immune … chronic inflammation in mid
and late childhood. This effect was consistently observed for GlycA, but not hsCRP, across 4 …

[HTML][HTML] Adverse childhood experiences and biomarkers of inflammation in a diverse cohort of early school-aged children

N Heard-Garris, MM Davis, R Estabrook, J Burns… - Brain, Behavior, & …, 2020 - Elsevier
… to examine inflammation as a mechanism of stress on … to describe the biological and
physiological embedding of ACEs … guidance on pediatric inflammatory data collection procedures. …

Early life stress, systemic inflammation, and neural correlates of implicit emotion regulation in adolescents

JP Yuan, TC Ho, SM Coury, R Chahal… - Brain, Behavior, and …, 2022 - Elsevier
… Thus, the biological embedding of stressors may lead to the … This study also found that
the effect of childhood ELS on … perspective, peripheral inflammatory processes could serve …

Biological embedding of experience: A primer on epigenetics

MJ Aristizabal, I Anreiter… - Proceedings of the …, 2020 - National Acad Sciences
… impact children’s future outcomes through biological embedding: the process whereby …
implicates miRNAs in susceptibility to stress-related phenotypes and their biological embedding. …