[HTML][HTML] Childhood trauma and dysregulation of multiple biological stress systems in adulthood: Results from the Netherlands Study of Depression and Anxiety …

E Kuzminskaite, CH Vinkers, BM Elzinga… - …, 2020 - Elsevier
… , IL-6, and cumulative inflammation), and cumulative markers across all stress systems. This
… as a confounding bias or a specific process via which CT impacts stress systems. In fact, a …

[HTML][HTML] Emotion regulation as a pathway connecting early life adversity and inflammation in adulthood: A conceptual framework

A Mathur, JC Li, SR Lipitz… - Adversity and Resilience …, 2022 - Springer
… as stressful or traumatic experiences endured in childhood or … , or activity in specific brain
regions, and inflammatory processes. … The biological embedding model proposes that ELA …

Childhood abuse histories predict steeper inflammatory trajectories across time

ME Renna, J Peng, MR Shrout, AA Madison… - Brain, behavior, and …, 2021 - Elsevier
… Analysis Methods. Linear mixed effects models were used to … Consistent with the biological
embedding model, this study … stress among our participants that ultimately influenced …

Early life adversity, inflammation, and immune function: An initial test of adaptive response models of immunological programming

K Cunningham, S Mengelkoch, J Gassen… - Development and …, 2022 - cambridge.org
… immune response to challenge (biological embedding model) or … inflammation and each (a)
childhood SES and (b) childhood … If inflammatory activity is an incidental byproduct of stress-…

Early childhood adversity, toxic stress, and the impacts of racism on the foundations of health

JP Shonkoff, N Slopen… - Annual Review of Public …, 2021 - annualreviews.org
… Acceleration of the aging process in childhood can be … between childhood trauma and three
key inflammatory markers … cultural racism and deeply embedded patterns of discrimination …

Linking the hemodynamic consequences of adverse childhood experiences to an altered HPA axis and acute stress response

KS Dempster, DD O'Leary, AJ MacNeil… - Brain, behavior, and …, 2021 - Elsevier
Biological embedding, believed to be rooted in dysfunction of … stress reactivity pertaining to
HPA axis function, inflammation, … atherosclerotic processes are initiated through macrophage …

Biological correlates of early life stressful events in major depressive disorder

RC Silva, E Maffioletti, M Gennarelli, BT Baune… - …, 2021 - Elsevier
… the childhood period on neurodevelopment and its biological … , gets embedded in the
functioning of the cells that regulate … Another inflammatory marker mediating childhood adversities …

[HTML][HTML] Stress genomics revisited: gene co-expression analysis identifies molecular signatures associated with childhood adversity

L Dieckmann, S Cole, R Kumsta - Translational psychiatry, 2020 - nature.com
… These long-term effects speak toward a biological embedding … of pro-inflammatory cytokines
in adults reporting childhood … our insights into molecular processes associated with a …

Pathways to inflammation in adolescence through early adversity, childhood depressive symptoms, and body mass index: a prospective longitudinal study of Chilean …

BM Reid, JR Doom, RB Argote… - Brain, behavior, and …, 2020 - Elsevier
… interpersonal stress was related to inflammation through the … stress-mediating epigenetic
and inflammatory processes that … adversity can become biologicallyembedded” to influence …

Adverse childhood experiences and depressive symptoms in later life: longitudinal mediation effects of inflammation

E Iob, R Lacey, A Steptoe - Brain, Behavior, and Immunity, 2020 - Elsevier
… of inflammation as a mediating mechanism through which ACEs may become biologically
embedded and … role of inflammation and other stress-related biological processes in different …