Advances in bioreactor systems for the production of biologicals in mammalian cells

R Sharma, STL Harrison, SL Tai - ChemBioEng Reviews, 2022 - Wiley Online Library
… nucleo bioreactor with tumbling impeller, Pad bioreactor, vertical wheel and rotating wall
bioreactor), and (5) membrane bioreactors (… In this article, these different bioreactor systems are …

[HTML][HTML] Bioreactor control systems in the biopharmaceutical industry: a critical perspective

S Mitra, GS Murthy - Systems Microbiology and Biomanufacturing, 2022 - Springer
… latest trends in control systems and automation of bioreactors in the … Section 2 gives an
overview of bioreactors and control … strategy for various bioreactor configurations and challenges …

Bioreactor design and validation for manufacturing strategies in tissue engineering

D Lim, ES Renteria, DS Sime, YM Ju, JH Kim… - Bio-design and …, 2022 - Springer
… specific bioreactor system for preconditioning and maturation prior to application in vivo. The
bioreactor system … The bioreactor system facilitates the delivery of nutrients and oxygen and …

[HTML][HTML] Development of novel bioreactor control systems based on smart sensors and actuators

B Wang, Z Wang, T Chen, X Zhao - Frontiers in bioengineering and …, 2020 - frontiersin.org
… of bioreactor control systems and discuss the properties of the novel FOCS for bioreactors
and … The current research on bioreactor control systems can be grouped into two aspects, with …

[HTML][HTML] Advanced 3D cell culture techniques in micro-bioreactors, part II: Systems and applications

B Altmann, C Grün, C Nies, E Gottwald - Processes, 2020 - mdpi.com
… -bioreactors we give a detailed description of the published work with regard to the existing
micro-bioreactor … with the respective systems. As an interesting detail, we found that micro-…

[HTML][HTML] An overview of drive systems and sealing types in stirred bioreactors used in biotechnological processes

C Schirmer, RW Maschke, R Pörtner, D Eibl - Applied microbiology and …, 2021 - Springer
… tank bioreactors are the most commonly used systems in biotechnological production processes.
Single-use and reusable systems … of impellers used in these systems have a significant …

Applications of novel bioreactor technology to enhance the viability and function of cultured cells and tissues

HW Hoyle, LA Smith, RJ Williams… - Interface …, 2020 - royalsocietypublishing.org
… In this study, we have developed a novel bioreactor system that enables flow of medium
and cell perfusion of 3D cell cultures to enhance the growth and maintenance of tissue-like …

[HTML][HTML] Advanced 3D cell culture techniques in micro-bioreactors, part I: a systematic analysis of the literature published between 2000 and 2020

C Grün, B Altmann, E Gottwald - Processes, 2020 - mdpi.com
… of eukaryotic 3D cell culture in micro-bioreactors within the last 20 years. … bioreactor
design including mode of cell stimulation/nutrient supply and materials used for the micro-bioreactors

Physically active bioreactors for tissue engineering applications

N Castro, S Ribeiro, MM Fernandes… - Advanced …, 2020 - Wiley Online Library
… of bioreactors that properly stimulate those materials and cells in vitro, creating an appropriate
biomimetic microenvironment, is developed to obtain active bioreactors… specific bioreactor

Working principle of typical bioreactors

P Jaibiba, SN Vignesh, S Hariharan - Bioreactors, 2020 - Elsevier
… working principle of different types of bioreactors, particularly those used in … bioreactors
dealt with in this chapter include aerobic bioreactors, anaerobic bioreactors, plug flow bioreactors