The CD36 and SR-A/CD204 scavenger receptors fine-tune Staphylococcus aureus-stimulated cytokine production in mouse macrophages

A Peruń, M Gębicka, R Biedroń, P Skalska… - Cellular …, 2022 - Elsevier
… They are recognized by heterodimers of Toll-like receptor (TLR) 2 with either TLR6 or TLR1
[… of ligand binding to CD36 and CD14 we performed experiments with recombinant receptors

Immunological mechanisms underlying sterile inflammation in the pathogenesis of atherosclerosis: Potential sites for intervention

R Truong, FG Thankam, DK Agrawal - Expert review of clinical …, 2021 - Taylor & Francis
… of sterile inflammation and the receptor complex of CD36-TLR4-… RAGE, similar to toll like
receptors (TLRs), are expressed on … decrease NLRP3 inflammasome assembly and activation […

CD36, a signaling receptor and fatty acid transporter that regulates immune cell metabolism and fate

Y Chen, J Zhang, W Cui, RL Silverstein - Journal of Experimental …, 2022 - rupress.org
… intracellular effectors CD36 must initiate assembly of a … It is possible that different ligands
create a variety of CD36 … Key role of CD36 in Toll-like receptor 2 signaling in cerebral …

[HTML][HTML] TLR2 and TLR4 surface and gene expression in white blood cells after fasting and oral glucose, lipid and protein challenges: influence of obesity and sex …

MÁ Martínez-García, M Ojeda-Ojeda… - Biomolecules, 2020 - mdpi.com
… of toll-like receptors 2 and 4 (TLR2 and TLR4) during fasting and … according to the
manufacturers instructions (BD Biosciences, San … Our results concerning monocyte CD36 and …

Hemin acts as CD36 ligand to activate down-stream signalling to disturb immune responses and cytokine secretion from macrophages

S Banesh, S Layek, V Trivedi - Immunology Letters, 2022 - Elsevier
… quantified as per the manufacturer's instructions. All the data … toll-like receptors and other
hemin responsive receptors, there … with CD36 triggers the association of CD36 with Toll like

TLR4 (toll-like receptor 4)-dependent signaling drives extracellular catabolism of LDL (low-density lipoprotein) aggregates

RK Singh, AS Haka, A Asmal… - … , and vascular biology, 2020 - Am Heart Assoc
… several receptors, LDLr (LDL receptor), SCARA1, and CD36, … Inhibition of PI3K abolishes
F-actin assembly at sites of … and a maladaptive sterile inflammatory response and provide …

[HTML][HTML] From classical to unconventional: the immune receptors facilitating platelet responses to infection and inflammation

I Gautam, Z Storad, L Filipiak, C Huss, CK Meikle… - Biology, 2020 - mdpi.com
… to possess functional toll like receptors that initiate immune … of ligands to CD36 initiates
signaling causing platelets to enter … activity, involving Toll like receptor 4. PLoS ONE 2017, 12, …

[HTML][HTML] The intriguing role of TLR accessory molecules in cardiovascular health and disease

T Bezhaeva, J Karper, PHA Quax… - Frontiers in …, 2022 - frontiersin.org
… Activation of Toll like receptors (TLR) plays an important role … which might point toward a role
in sterile inflammation (25). … Recent studies revealed that CD36 induces the assembly of the …

Tolllike receptors: general molecular and structural biology

P Behzadi, HA García-Perdomo… - Journal of Immunology …, 2021 - Wiley Online Library
CD36 molecule can promote immune responses against some ligands of TLR2-TLR6 and
mediates inflammatory … role in assembling fliC subunits and their polymerization into a helical …

[HTML][HTML] The past and present lives of the intraocular transmembrane protein CD36

R Yang, Q Liu, M Zhang - Cells, 2022 - mdpi.com
Toll-like receptor (TLR) 4 and TLR6 accessory receptor [15], … The role of CD36 ligands and
signal transduction pathways … Although involved in the sterile inflammation of the retina, CD36