Mitochondria-associated membrane-modulated Ca2+ transfer: A potential treatment target in cardiac ischemia reperfusion injury and heart failure

Y Gong, J Lin, Z Ma, M Yu, M Wang, D Lai, G Fu - Life Sciences, 2021 - Elsevier
… , excessive and unresolved UPR elicits uncontrolled cell death [76]. … Meanwhile, the protective
role of preconditioning … They went further to suggest that this paradox may be attributed to …

Effect of hyperglycaemia and diabetes on acute myocardial ischaemia–reperfusion injury and cardioprotection by ischaemic conditioning protocols

C Penna, I Andreadou, M Aragno… - British journal of …, 2020 - Wiley Online Library
… an increased preconditioning stimulus in diabetic hearts. This … of diabetes, the heart is in a
paradoxical state of protection. … to abrogate cardioprotection elicited by limb RIC in a rat acute …

Nitrite and myocardial ischaemia reperfusion injury. Where are we now?

K Griffiths, JJ Lee, MP Frenneaux, M Feelisch… - Pharmacology & …, 2021 - Elsevier
… future for nitrite as a pre-conditioning intervention in man. … in a paradoxical phenomenon
termed myocardial ischaemia … intra-arterial infusions of nitrite elicit a substantial vasodilatory …

Preclinical multi-target strategies for myocardial ischemia-reperfusion injury

Y Li, Y Gao, G Li - Frontiers in Cardiovascular Medicine, 2022 - frontiersin.org
… activation of the 2Na + /Ca 2+ exchanger, leading to calcium … postconditioning (SPC) protects
normal rat hearts from IRI, … mononucleotide preconditioning in aging hearts restores the …

[HTML][HTML] Ischemia preconditioning alleviates ischemia/reperfusion injury-induced coronary no-reflow and contraction of microvascular pericytes in rats

Q Li, Z Guo, C Wu, Y Tu, Y Wu, E Xie, C Yu, W Sun… - Microvascular …, 2022 - Elsevier
… network of functionally distinct vessel segments … precondition occlusion protected the heart
against I/R injury by stimulating cardiac A 1 receptors, and reducing Ca 2+ overload damage

Selective vulnerability of hippocampal CA1 and CA3 pyramidal cells. Collation of possible pathomechanisms for selective damage known to date from various study …

AM Einenkel, A Salameh - osf.io
paradox), pH neutralization (pH paradox), further increase in … Ischemic and pharmacological
(NMDA) preconditioningCA2/lateralCA3 dominant death of neurons in younger rats (…

[HTML][HTML] The Remaining Conundrum of the Role of the Na+/H+ Exchanger Isoform 1 (NHE1) in Cardiac Physiology and Pathology: Can It Be Rectified?

M Karmazyn, GN Pierce, L Fliegel - Reviews in Cardiovascular …, 2022 - imrpress.com
… of studies to again elicit significant cardioprotection during … during ischemic pre-conditioning
[259] or the Ca 2 + paradox … extensive protection in both isolated rat hearts as well as in rats

Pharmacological tuning of adenosine signal nuances underlying heart failure with preserved ejection fraction

A Campos-Martins, B Bragança… - Frontiers in …, 2021 - frontiersin.org
… calcium (Ca 2+ ) mobilization; both intracellular Ca 2+ … , angiogenesis and protection
from ischemic preconditioning, … Both in cardiomyocytes and in intact hearts of rats subjected …

Cerebral ischemia/reperfusion injury and pharmacologic preconditioning as a means to reduce stroke-induced inflammation and damage

H Yang, C Qi, F Su, W Shan, A Guo, J Wu… - Neurochemical …, 2022 - Springer
… Cerebral I/R elicited inflammatory responses characterized … , which is the so-called French
paradox. This appears to be attributed … Isolated perfused rat hearts were pretreated with 10 µM …

… posttreatments with Omegaven and ATP in a four-chamber isolated working swine heart model: implications for cardiac interventions, cardiac transplantation and ex …

MS Seewald - 2020 - repo.bibliothek.uni-halle.de
… Ischemic preconditioning has been utilized to protect the heart … in our experimental studies
also elicited beneficial effects. … both preconditioning and postconditioning in rat hearts on the …