Genetic impacts on DNA methylation: research findings and future perspectives

S Villicaña, JT Bell - Genome biology, 2021 - Springer
… in characterizing the human genetic basis of DNA methylation … is based on trait comparison
between monozygotic (MZ) twin … DNA methylation level at a CpG site is the response variable

Equivalent DNA methylation variation between monozygotic co-twins and unrelated individuals reveals universal epigenetic inter-individual dissimilarity

B Planterose Jiménez, F Liu, A Caliebe… - Genome biology, 2021 - Springer
… to environmental factors promote methylation divergence over … in the cryptic promoter results
in variable expression of the … The parameter epsilon (ε), which characterizes the resolution …

Genetic and in utero environmental contributions to DNA methylation variation in placenta

S Chatterjee, M Ouidir… - … Molecular Genetics, 2021 - academic.oup.com
… and functionally characterize placental variably methylated … Descriptive statistics of the 12
prenatal environmental factors … genome with highly variable CpG methylation, using a strategy …

Identification, heritability, and relation with gene expression of novel DNA methylation loci for blood pressure

Y Huang, M Ollikainen, M Muniandy, T Zhang… - …, 2020 - Am Heart Assoc
variable, DNA methylation as the independent variable, age, … The monozygotic twins of
each pair (MZ twins) have identical … contributions of genetic and environmental factors to the …

DNA methylation in the diagnosis of monogenic diseases

F Cerrato, A Sparago, F Ariani, F Brugnoletti, L Calzari… - Genes, 2020 - mdpi.com
… that DNA methylation can be influenced by environmental factors… BWS is characterized by
variable clinical features, which may … testing is not necessarily identical to the one indicated for …

Genetic and environmental determinants of O6-methylguanine DNA-methyltransferase (MGMT) gene methylation: a 10-year longitudinal study of Danish twins

L Wang, A Mohammadnejad, W Li, J Lund, S Li… - Clinical …, 2021 - Springer
… affected by environmental factors, as well as genetic variation… in monozygotic (MZ) twin
pairs who share their genetic … GWAS on DNA methylation levels of our identified heritable …

Rearing environment affects the genetic architecture and plasticity of DNA methylation in Chinook salmon

CJ Venney, KW Wellband, DD Heath - Heredity, 2021 - nature.com
Characterizing genetic and environmental influences on methylation is critical for future
studies on DNA methylationDNA methylation is highly variable, even within lineages of clonal …

[HTML][HTML] Genome-wide DNA methylation patterns associated with general psychopathology in children

J Rijlaarsdam, ED Barker, C Caserini… - Journal of psychiatric …, 2021 - Elsevier
… Third, we explored potential genetic and environmental influences on DNAm. … characterizing
additive genetic influences as opposed to shared and non-shared environmental influences

Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation

JL Min, G Hemani, E Hannon, KF Dekkers… - … genetics, 2021 - nature.com
Characterizing genetic influences on DNA methylation (DNAm) provides an opportunity to
understand mechanisms underpinning gene regulation and disease. In the present study, we …

Genomic and phenomic insights from an atlas of genetic effects on DNA methylation

JL Min, G Hemani, E Hannon, KF Dekkers… - MedRxiv, 2020 - medrxiv.org
Characterizing genetic influences on DNA methylation (DNAm) provides an … results of DNA
methylation-quantitative trait loci (mQTL) analyses on 32,851 participants, identifying genetic