… shown considerable potential for the evaluation of ocular irritancy. Organotypic models
have emerged as the most promising alternative approaches to the eye irritation assessment, …

… One of the approaches commonly used to increase the residential time of … Once the NPs
were characterized and their in-vitro stability assessed for potential ophthalmic delivery and …

… (DEX)-containing eye drops. The application of eye drops is challenging due to the high
number of daily administrations. In this study, mucoadhesive nanoparticles (NPs) were …

… Polymeric nanospheres (NPs) loading antibiotic drugs represent the most promising
approach to eradicate ocular infections and to treat pathogen resistance. In this study, we have …

… , ibrutinib, was loaded into chitosan/sulfobutylether-β-cyclodextrin nanoparticles (NPs). NPs
… This study provided a worthy approach for the development of new formulation of tyrosine …

… 30 μL) of eye drop formulation can be instilled in the eye. As a … method, yet not an ideal
one as other limitations arise: first-pass metabolism, side effects, blood–ocular barriers, low eye …

Acyclovir is the gold standard drug for herpes simplex virus type 2 (HSV-2) infection treatment.
Vaginal topical therapy with acyclovir is hampered due to its poor bioavailability, low …

… The most extensively researched complexation approaches fall within either phospholipid- …
deionized water (aqueous method) or water-ethanol mixture (co-solvent method) to prepare …

… Econazole nitrate release from optimized chitosan/sulfobutylether-β-cyclodextrin nanoparticles
was controlled with approximately 50% of the original amount released over an 8 hr …

… The in vivo safety profile of silica nanoparticles has been previously … approach for the
ocular topical delivery of drugs [22,23]. Using silica nanoparticles as drug carriers for ocular …