Functional Analysis of a Frontal miRNA Cluster Located in the Large Latency Transcript of Pseudorabies Virus

W Hoffmann, AD Lipińska, K Bieńkowska-Szewczyk - Viruses, 2022 - mdpi.com
… a non-coding region called the Latency Associated Transcript (… a primary precursor of clustered
microRNAs (miRNAs, miRs) … , a cluster of eleven viral miRNAs has been identified in the …

The role of latency-associated transcripts in the latent infection of pseudorabies virus

J Deng, Z Wu, J Liu, Q Ji, C Ju - Viruses, 2022 - mdpi.com
… , the miRNAs of most herpesviruses have been identified, … of miRNAs which are usually
clustered in the viral genome. The viral miRNAs are limited to LAT sites or adjacent regions and …

Regulation of latency and reactivation by human cytomegalovirus miRNAs

NL Diggins, RL Skalsky, MH Hancock - Pathogens, 2021 - mdpi.com
… Of the over 250 identified viral miRNAs to date, most are … The first herpesvirus miRNAs were
identified in cells latently … in the expression of the latency-associated gene UL138. UL138 …

MicroRNA regulation of human herpesvirus latency

S Chen, Y Deng, D Pan - Viruses, 2022 - mdpi.com
… H24 of HSV-2 are clustered within the latency-associated transcript (LAT) region, while miR-H1
… Another set of techniques needed are those for identifying miRNA targets. Bioinformatics …

[PDF][PDF] The Role of Latency-Associated Transcripts in the Latent Infection of Pseudorabies Virus. Viruses 2022, 14, 1379

J Deng, Z Wu, J Liu, Q Ji, C Ju - … Virus (Volume I) Chief Editor: Prof …, 2022 - mdpi.com
miRNAs of most herpesviruses have been identified, including PRV. However, the specific
function of PRV miRNAs … of miRNAs which are usually clustered in the viral genome. The viral …

Cis regulation within a cluster of viral microRNAs

M Vilimova, M Contrant, R Randrianjafy… - Nucleic acids …, 2021 - academic.oup.com
within this large viral miRNA cluster. We observed that the ten miRNA hairpins from the KSHV
intronic cluster are … Positive clones were identified by sequencing (GATC Biotech, France). …

MicroRNAs expressed by human cytomegalovirus

L Zhang, J Yu, Z Liu - Virology journal, 2020 - Springer
… [4], at least 48,000 mature miRNAs have been identified [5]. … of latency-associated HCMV
transcripts including miRNAs … of miRNA gene prediction combined with small-RNA cloning

A comparison of pseudorabies virus latency to other α-Herpesvirinae subfamily members

J Chen, G Li, C Wan, Y Li, L Peng, R Fang, Y Peng… - Viruses, 2022 - mdpi.com
… restricted to a small region of the viral genome that is named the latency-associated transcript
(LAT) … In the 4.6 kb region, a cluster of 11 miRNA genes is identified by deep sequencing in …

HSV-1 miRNAs are post-transcriptionally edited in latently infected human ganglia

A Zubković, C Gomes, A Parchure, M Cesarec… - Journal of …, 2023 - Am Soc Microbiol
… or within the region encoding the latency-associated transcripts (… We also sequenced
amplicons obtained from the cloned … We identified 17 potential binding sites for miR-H2-3p, …

Herpesviral latency—common themes

M Weidner-Glunde, E Kruminis-Kaszkiel… - Pathogens, 2020 - mdpi.com
miRNAs could be detected only at specific time points, ie, at … gene, ORF4 were identified in
latently infected human ganglia … Recently identified VZV latency-associated transcript (VLT) …