… to their potential in predicting healthspan and application in … outperforms DNAm GrimAge in
its estimation of lifespan and has … similar age predictions for both low and highly proliferative …

… = 0.13) and somewhat more strongly correlated with age accel… health- span and lifespan
over and above existing DNA meth… the GrimAge clock, which was developed to predict mortality …

… of age predictors utilising DNA methylation have been developed… GrimAge overall had the
best performance; it predicted the … GrimAge also outperformed other clocks for predicted death …

… has documented healthspan and lifespan disparities across … that can predict a person’s
chronological age from DNA methylation … In the case of the GrimAge clock, a set of physiological …

… ) was defined by regressing DNAm GrimAge on chronological age and was used in age-…
and GrimAge are excellent biological age estimators for predicting healthspan and lifespan, …

… DNA methylation levels at specific CpG sites that are highly … from the regression of DNA
methylation age on calendar age is … was so strongly associated with health span and life span is …

… to predict chronological age and the original versions of the PhenoAge and GrimAge clocks
… DunedinPACE has high test–retest reliability and shows strong associations with healthspan …

… DNA methylation based (DNAm) GrimAge for predicting mortality … GrimAge across a broad
category of lifespan and healthspan … Here we greatly increased the sample size to n=13,420 …

… to predict two aspects of biological age: healthspan and … In the time since this 2016
meta-analysis, new DNA methylation … For example, a metric known as GrimAge can strongly …

… than the Horvath clock that may be beneficial when it comes to predicting lifespan (16,18). …
It was thus highly likely that the scope and size of this review would already be large. Many of …