A collaborative exercise on DNA methylation-based age prediction and body fluid typing

JE Lee, JM Lee, J Naue, J Fleckhaus… - Forensic Science …, 2022 - Elsevier
… A tissue-wide clock which enables age prediction across a broad spectrum of …
methylation-based body fluid identification steps followed by age prediction using the set of markers …

Combining current knowledge on DNA methylation-based age estimation towards the development of a superior forensic DNA intelligence tool

A Aliferi, S Sundaram, D Ballard… - Forensic Science …, 2022 - Elsevier
… The estimation of chronological age from biological fluids … Since methods for DNA
methylation-based age prediction … has focused on forensically-relevant tissues as well as targeted …

Artificial neural network, predictor variables and sensitivity threshold for DNA methylation-based age prediction using blood samples

Z Thong, JYY Tan, ES Loo, YW Phua, XLS Chan… - Scientific reports, 2021 - nature.com
DNA intelligence, one example being the ability to predict the chronological age of the donor
of a body fluid … , using 353 CpGs to predict age in 51 different tissue types with an improved …

Chronological age prediction: developmental evaluation of DNA methylation-based machine learning models

H Fan, Q Xie, Z Zhang, J Wang, X Chen… - … in Bioengineering and …, 2022 - frontiersin.org
tissues, and employing methylation levels of strongly age-… four different ML models for
chronological age prediction in the … sets are concordant in four different ML models (all p > 0.05), …

DNA methylation-based age prediction using cell separation algorithm

NS Jaddi, MS Abadeh - Computers in Biology and Medicine, 2020 - Elsevier
… three forms of age prediction problems from two body fluids (blood … tissues by massive parallel
sequencing was proposed in … prediction models for forensic age prediction based on DNA

Characterization of DNA methylation-based markers for human body fluid identification in forensics: a critical review

F Kader, M Ghai, AO Olaniran - International journal of legal medicine, 2020 - Springer
… relevant tissues (tDMRs) and body fluids. Diverse … body fluid identification needs to be
assessed in the long term. Here, we discuss the current status of reported DNA methylation-based

Age prediction in living: Forensic epigenetic age estimation based on blood samples

HC Dias, E Cunha, FC Real, L Manco - Legal Medicine, 2020 - Elsevier
… KLF14 are associated with chronological age in several tissues such as blood, buccal swabs
and teeth, for developing several forensic highly accurate age-prediction models (APMs) […

… and construction of a random forest prediction model for the accurate tissue origin identifications of body fluids involving young and middle-aged group of Chinese …

Y Fang, M Chen, M Cai, F Lei, B Zhu - International Journal of Legal …, 2023 - Springer
… a random forest classification prediction model was constructed for body fluid identification
in … from Chinese Han volunteers aged 20–45. The age correlation of these body fluid-specific …

[HTML][HTML] Progress in Age Estimation Based on DNA Methylation

Y Huang, S Qu, Y Xiao, H Jian… - Journal of Forensic …, 2023 - journals.lww.com
DNA methylation-based age estimation into practice is expected to enhance the accuracy
and reliability of age … the cross-tissue age prediction ability of existing CpGs in single tissues. …

Age estimation using DNA methylation technique in forensics: a systematic review

C Maulani, EI Auerkari - Egyptian Journal of Forensic Sciences, 2020 - Springer
… This review aims to address the DNA methylation-based age … used in studies with different
body fluids and teeth (Fig. 7). … significantly disparate between different tissues, depending on …