[HTML][HTML] DNA methylation biomarkers in aging and age-related diseases

Y Salameh, Y Bejaoui, N El Hajj - Frontiers in Genetics, 2020 - frontiersin.org
… as biomarkers of disease. We only display diseases/conditions where epigenetic age
acceleration … The focus of this review is on methylation-based biomarkers therefore we will mainly …

Assessment of epigenetic clocks as biomarkers of aging in basic and population research

ME Levine - The Journals of Gerontology: Series A, 2020 - academic.oup.com
biomarkers is not how well they predict chronological time, but rather how well they predict
aging outcomes, above and beyond age itself. … age, do those with higher epigenetic age look …

DNA methylation age as a biomarker for cancer

CHE Lau, O Robinson - International Journal of Cancer, 2021 - Wiley Online Library
… GrimAge is a composite predictor of lifespan modelled on seven DNA methylation-based
, all of blood-based epigenetic clock epidemiological studies we identified have reported at …

The use of DNA methylation clock in aging research

X He, J Liu, B Liu, J Shi - Experimental Biology and Medicine, 2021 - journals.sagepub.com
DNA methylation-based biomarkers to be the most promising biomarker for aging. Herein we
… methylation, also known as epigenetic age or more precisely DNA methylation age, reflects …

DNA methylation-based age clocks: From age prediction to age reversion

R Noroozi, S Ghafouri-Fard, A Pisarek… - Ageing Research …, 2021 - Elsevier
… in this review including epigenetic age estimator (epigenetic age clock), epigenetic age (DNA
methylation age), phenotypic age, and epigenetic age acceleration are defined as follows. …

DNA methylation clocks and their predictive capacity for aging phenotypes and healthspan

T Bergsma, E Rogaeva - Neuroscience insights, 2020 - journals.sagepub.com
… The reduced precision of DNAm clocks in cell cultures was solved by a recently developed
DNAm clock that accurately measures the epigenetic age of fibroblasts, keratinocytes, as well …

Epigenetic clock: A promising biomarker and practical tool in aging

R Duan, Q Fu, Y Sun, Q Li - Ageing Research Reviews, 2022 - Elsevier
… overview of the epigenetic clock as a biomarker of aging and a useful tool to manage
healthy aging. In this … The Hannum’s epigenetic clock, a single-tissue DNA methylation-based

DunedinPACE, a DNA methylation biomarker of the pace of aging

DW Belsky, A Caspi, DL Corcoran, K Sugden… - Elife, 2022 - elifesciences.org
… This paper presents a new DNA methylation- based biomarker of aging: DunedinPACE.
This biomarker is an … For each epigenetic clock, we calculated the measure referred to as …

Integrating DNA methylation measures of biological aging into social determinants of health research

L Raffington, DW Belsky - Current Environmental Health Reports, 2022 - Springer
… applications of DNA methylationbased measures of biological aging to … in healthy aging.
Early studies applying these new … DNA methylation-based biomarkers and the epigenetic clock

[HTML][HTML] Counteracting aged DNA methylation states to combat ageing and age-related diseases

A Reale, S Tagliatesta, G Zardo, M Zampieri - Mechanisms of Ageing and …, 2022 - Elsevier
Epigenetic age does not only estimate chronological age but can also predict the risk of
chronic diseases and mortality. Epigenetic age is … metrics of biological age. Initial evidence has …