Neuromolecular interactions guiding homeostatic mechanisms underlying healthy ageing: A view from computational microscope
S Saha, P Chakraborty, A Naskar, D Roy, A Banerjee - bioRxiv, 2023 - biorxiv.org
… over the lifespan accompanied by reorganization in … the tuning of glutamate and GABA
concentration over a very slow … So an overarching question arises, whether the age-related …
concentration over a very slow … So an overarching question arises, whether the age-related …
Neuroprotective role of dietary supplementation with omega-3 fatty acids in the presence of basal forebrain cholinergic neurons degeneration in aged mice
D Cutuli, E Landolfo, D Decandia, A Nobili… - International Journal of …, 2020 - mdpi.com
… [23], when deterioration in neuronal function and decline in … a significant CA3 neuronal
loss accompanied by microglial … neurogenesis tends to have an age-related decline [134], the …
loss accompanied by microglial … neurogenesis tends to have an age-related decline [134], the …
Effect of High-Oleic Peanut Intake on Aging and Its Hippocampal Markers in Senescence-Accelerated Mice (SAMP8)
K Igarashi, D Kurata - Nutrients, 2020 - mdpi.com
… were decreased by feeding of the samples, and the GABA/… , which accompanies aging [3].
The improvement in cognitive … in the brain and regulates neuronal functions, including the …
The improvement in cognitive … in the brain and regulates neuronal functions, including the …
[HTML][HTML] Long-Term Acetylcholinesterase Depletion Alters the Levels of Key Synaptic Proteins while Maintaining Neuronal Markers in the Aging Zebrafish (Danio rerio) …
… on the progression of age-related cognitive decline in zebrafish [… , female subjects had lower
levels of GABA-a1 as compared … of mutants was accompanied by significant modulations in …
levels of GABA-a1 as compared … of mutants was accompanied by significant modulations in …
GABAA Receptors in the Mongolian Gerbil: a PET Study Using [18F]Flumazenil to Determine Receptor Binding in Young and Old Animals
M Kessler, M Mamach, R Beutelmann… - Molecular imaging and …, 2020 - Springer
… auditory system involving the GABAergic system accompany age-related hearing loss. Such
… age-related changes in GABA A receptor binding indicating a substantial decrease in GABA …
… age-related changes in GABA A receptor binding indicating a substantial decrease in GABA …
DNMT1-dependent regulation of cortical interneuron function and survival
D Pensold, G Zimmer-Bensch - Neural regeneration research, 2021 - journals.lww.com
… The different types of GABA-expressing interneurons mediate … So, the observed age-related
changes in the DNA … reduction in the cerebral cortex, which was accompanied by reduced …
changes in the DNA … reduction in the cerebral cortex, which was accompanied by reduced …
Changes of Signaling Pathways in Hypothalamic Neurons with Aging
PM Masliukov - Current Issues in Molecular Biology, 2023 - mdpi.com
… The aging process in the hypothalamus is accompanied by disturbed … a possible cause for
the age-related decrease in GH level in … GABA-ergic and BDNF-expressing neurons of the …
the age-related decrease in GH level in … GABA-ergic and BDNF-expressing neurons of the …
Amyloid β-Oligomers Inhibit the Nuclear Ca2+ Signals and the Neuroprotective Gene Expression Induced by Gabazine in Hippocampal Neurons
P Lobos, I Vega-Vásquez, B Bruna, S Gleitze, J Toledo… - Antioxidants, 2023 - mdpi.com
… effects associated with different age-related diseases [5,6,7]. … the GABA A receptor antagonist
GBZ, which, by decreasing the … mediated by GBZ is accompanied by an increase in the …
GBZ, which, by decreasing the … mediated by GBZ is accompanied by an increase in the …
Direct Conversion of Human Skin Fibroblasts into induced Neurons: A Model to Study Age-Related Synaptic Dysfunctions
CC Ferreira - 2023 - repositorio.ul.pt
… Our results demonstrated a decrease in fibroblast marker … , or gamma-aminobutyric acid
(GABA), the most abundant inhibitory … This was accompanied by an mGluR5-dependent NMDAR …
(GABA), the most abundant inhibitory … This was accompanied by an mGluR5-dependent NMDAR …
Translational control in aging and neurodegeneration
… age-related changes in protein degradation, alterations in the efficiency and fidelity of protein
synthesis with aging are less well … impacts on neuronal function and predispose neurons to …
synthesis with aging are less well … impacts on neuronal function and predispose neurons to …