… that diagnostic overlap would be mirrored at the genetic level … using collateral gene expression
data, such as single-cell RNA … genomic factors defined primarily by compulsive disorders […

… diagnostic spectrum. We begin by estimating several potential … Enrichment is defined as the
ratio of the proportion of genome-… genes and genes with low expression, for the 14 cell types, …

… ” of the genetic architecture of psychiatric diseases to yield … the substantial heritability of
psychiatric disorders and vastly … results for psychiatric illnesses connect to brain cell types (ie, …

… A genome-wide significant locus was defined as the region … a direct GWAS of SA within
psychiatric diagnosis (Supplement 1), … to control for the genetic effects of psychiatric disorders. …

… in power and genetic architecture between psychiatric disorders. … , correcting separately
for gene sets, tissues or cell types, we … A user-defined gene list can be inputted to SynGO to …

… common genetic architecture among psychiatric disorders … then gain biological insights by
identifying genes, tissues, cells… information of disease nor which kind of cell type is involved. …

… and psychiatric diseases have high degrees of genetic and … protein misfolding disorders),
or pathologically defined ‘… rapid progress in human genetics and genomics, yielding new …

… , pathways, tissues, and cell types relevant for phenotype … Clinically, specific ASD diagnoses
tend to be defined based on … the polygenic architecture of psychiatric disorders. However, …

… transcend the diagnostic boundaries of psychiatric disorders. … successes in identifying
genes with a large role in disease (such … Thus, tremendous numbers of animal studies and cell-…

… of attempting to define psychiatric disorders (or the disorders listed in … During meiosis (the
process of cell division that produces … , functioning, and genetic risk architecture, and the many …