Interleukin-1

TR Aksamit, GW Hunninghake - Cytokines of the Lung, 2022 - taylorfrancis.com
monocytes/ macrophages for the production of IL-l in various disease states. Other agents can
attenuate IL-l production. … and interleukin 1 production by human monocyte macrophages. …

[HTML][HTML] What is IL-1 for? The functions of interleukin-1 across evolution

D Boraschi - Frontiers in immunology, 2022 - frontiersin.org
control system, which can inhibit IL-1 effects at various levels and dampen its activity once
… by many cell types, and mainly released by monocytes and macrophages, and is present at …

[HTML][HTML] Profiling the course of resolving vs. persistent inflammation in human monocytes: the role of IL-1 family molecules

P Italiani, E Mosca, G Della Camera, D Melillo… - Frontiers in …, 2020 - frontiersin.org
macrophages are more involved in phagocytosis and in recruiting other effector cells, while
recruited blood monocytes … culture monocytes/macrophages can still produce inflammation-…

Advances on the Role and Applications of Interleukin-1 in Tuberculosis

D Silvério, R Gonçalves, R Appelberg, M Saraiva - MBio, 2021 - Am Soc Microbiol
… Inflammatory monocytes, macrophages, and dendritic cells all … macrophages, implying
that IL-1 production may be differentially regulated within different myeloid subsets by different

[HTML][HTML] Interleukin-1 as innate mediator of T cell immunity

B Van Den Eeckhout, J Tavernier, S Gerlo - Frontiers in immunology, 2021 - frontiersin.org
… relied on the generation of monocyte-derived DCs (moDCs) … a Mafb-expressing macrophage
progenitor, whereas dermal … the different cellular targets of IL-1 possibly regulate different

Interleukin-1 and the inflammasome as therapeutic targets in cardiovascular disease

A Abbate, S Toldo, C Marchetti, J Kron… - Circulation …, 2020 - Am Heart Assoc
produced not only by monocytes and macrophages but also by neutrophils. IL-1α is quite
different; … In healthy subjects, IL-1β gene expression is low or absent in blood monocytes but is …

[HTML][HTML] The good and the bad: Monocytes' and macrophages' diverse functions in inflammation

J Austermann, J Roth, K Barczyk-Kahlert - Cells, 2022 - mdpi.com
… a pivotal role in the regulation of inflammation. … monocyte and macrophage adaptation to
rapidly changing microenvironmental conditions and discussed different forms of macrophage

[HTML][HTML] Interleukin 1α: a comprehensive review on the role of IL-1α in the pathogenesis and treatment of autoimmune and inflammatory diseases

G Cavalli, S Colafrancesco, G Emmi, M Imazio… - Autoimmunity …, 2021 - Elsevier
… Members of the interleukin 1 (IL-1) family of cytokines are … by cells in order to induce a
change in the function of different, … myeloid cells (ie monocytes, macrophages) expressing the IL-…

Neuronal interleukin-1 receptors mediate pain in chronic inflammatory diseases

B Mailhot, M Christin, N Tessandier… - Journal of Experimental …, 2020 - rupress.org
… cell populations, namely monocytes/macrophages and neutrophils, we next … difference in
disease initiation and its progression in Trpv1 Cre ::Il1r1 fl/fl mice compared with their control

[HTML][HTML] Interleukin-1β and cancer

C Rébé, F Ghiringhelli - Cancers, 2020 - mdpi.com
… , which in turn activates interleukin-1 receptor-associated … -1β increases macrophage
recruitment by allowing monocyte … In melanoma, production of VEGF and other proangiogenic …