RTS,S/AS01 malaria vaccine (Mosquirix®): a profile of its use

YY Syed - Drugs & Therapy Perspectives, 2022 - Springer
… In a phase 3 trial, RTS,S/AS01 showed vaccine efficacy … First results from large pilot
implementation in Africa show … from a phase 3 trial (NCT01148459) in children with WHO stage 1 …

Seasonal vaccination with RTS, S/AS01E vaccine with or without seasonal malaria chemoprevention in children up to the age of 5 years in Burkina Faso and Mali: a …

A Dicko, JB Ouedraogo, I Zongo, I Sagara… - The Lancet Infectious …, 2024 - thelancet.com
… in infants and children in Africa: final results of a phase 3, … with RTS,S/AS01 E during the
first 3 years of the study, all of whom … recorded in the RTS,S/AS01 E phase 3 trial were chance …

RTS, S/AS01E malaria vaccine induces IgA responses against CSP and vaccine-unrelated antigens in African children in the phase 3 trial

R Suau, M Vidal, R Aguilar, G Ruiz-Olalla… - Vaccine, 2021 - Elsevier
children (age 5–17 months old at first vaccination) from the RTS,S/AS01 E phase 3 clinical
trial who received 3 … that this could have an impact on protective immunity to malaria [35]. Little …

RTS, S/AS01 malaria vaccine—proven safe and effective?

A Björkman, CS Benn, P Aaby… - The Lancet Infectious …, 2023 - thelancet.com
… The evidence base included phase 3 trials in seven African … dose in infants and children in
Africa: final results of a phase 3, … incidence was highest during the first year, and the higher …

Efficacy of RTS, S/AS01E malaria vaccine administered according to different full, fractional, and delayed third or early fourth dose regimens in children aged 5–17 …

AM Samuels, D Ansong, SK Kariuki, S Adjei… - The Lancet Infectious …, 2022 - thelancet.com
… efficacy for fractional-dose versus full-dose regimens of RTS,S/AS01. We report first
results of an ongoing trial assessing different fractional-dose regimens in children, in natural …

Antibody responses to the RTS,S/AS01E vaccine and Plasmodium falciparum antigens after a booster dose within the phase 3 trial in Mozambique

L Sanchez, M Vidal, C Jairoce, R Aguilar, I Ubillos… - npj Vaccines, 2020 - nature.com
… has been associated with protection in African children 12 , and C-… We describe for the first
time the long-term RTS,S/AS01 E … The analysis of the phase 3 clinical trial found that children

Towards eradication of malaria: is the WHO's RTS, S/AS01 vaccination effective enough?

N Arora, LC Anbalagan, AK Pannu - Risk Management and …, 2021 - Taylor & Francis
… the encouraging results of early trials, a phase III randomized trial of RTS,S/AS01 vaccine (a
… the feasibility of delivering four doses in children in three African countries - Malawi, Ghana, …

Acceptance, availability, and feasibility of RTS, S/AS01 malaria vaccine: a review

H Mumtaz, A Nadeem, W Bilal, F Ansar… - Immunity …, 2023 - Wiley Online Library
… forward in creating a malaria vaccine for children in Africa. … the malaria vaccine involves
administering three initial doses at … findings of Phase 3, individually randomized, controlled study

Mosquirix™ RTS, S/AS01 vaccine development, immunogenicity, and efficacy

AY Nadeem, A Shehzad, SU Islam, EA Al-Suhaimi… - Vaccines, 2022 - mdpi.com
… , the malarial vaccine RTS, S/AS01 was tested in seven Africanpreliminary investigations
with the RTS, S/AS01 vaccinestudy, children were inoculated with alternate shots of RTS, …

… , malaria, mortality and other health outcomes in infants and young sub-Saharan African children prior to the introduction of the RTS,S/AS01E malaria vaccine

Malaria journal, 2021 - Springer
… of infants and children living in malaria-endemic countries, and is the firststudy enrolled
children not vaccinated with RTS,S/AS01 E in three study sites of moderate-to-high malaria