… of the FFQ on the genetic analysis of dietary habits. Second, … the largest genetic cohorts in
Japan, it is difficult currently to … function for binominal or quantitative traits, respectively. Age, …

… of GWASs in the Japanese population, we identified 519 … European dataset across binary
and quantitative traits (Methods). … of human complex traits in terms of populations and scope of …

… variation of diverse polygenic diseases and quantitative traits… identified 38 complex traits
whose genetic variation regulates … and serum samples from 12 medical institutions in Japan. …

… Since the genetic architecture is different according to trait 33 , the PRS differences need to
… of complex human traits. To this end, we performed GWASs of 45 quantitative traits on the …

… links IMD GWAS variants to susceptible genes, cell types, … Expression quantitative trait loci
(eQTL) analysis revealed … variants in Europeans and it was difficult to fine-map causal eQTL …

… study provides multiple insights into the etiology of complex traits, and highlights the importance
of conducing genetic … (GTEx) database of expression quantitative trait loci (eQTL) 33 . …

… In order to identify complex traits and diseases that share … traits associated with molecular
quantitative trait loci for the … Some of the statistical genetic analyses we carry out utilise data …

… (quantified through bulk and single-cell methods), gene regulation and other molecular
quantitative trait studies, … Another challenge in gene regulatory region analysis is the ability to link …

… analysis of 45 complex traits We performed genome-wide association analyses of 45
clinically-relevant quantitative traits … as new loci identified in the Japanese population (N = 332). Of …

… advances in genetic analysis shed light on the polygenic architecture of complex traits, …
Integration of genomic data with other omics data can elucidate quantitative trait locus (QTL) …