Environmental triggering of type 1 diabetes autoimmunity

P Houeiss, S Luce, C Boitard - Frontiers in Endocrinology, 2022 - frontiersin.org
… B-cells modify their expression of homing genes and migrate back … genes that directly drive
immune interactions with … triggers autoimmune activation on genetically susceptible genetic

Lifestyle or environmental influences and their interaction with genetic susceptibility on the risk of LADA

S Carlsson - Frontiers in Endocrinology, 2022 - frontiersin.org
… promotes autoimmunity and adds to the genetically induced … However, the excess risk of
type 1 diabetes related to intake of red … as to whether such factors may modify the risk of LADA. …

Functional impact of risk gene variants on the autoimmune responses in type 1 diabetes

C Gootjes, JJ Zwaginga, BO Roep… - Frontiers in immunology, 2022 - frontiersin.org
genetic risk and the intensity of the peripheral autoimmune … ) illustrating the interaction between
genes and environment that … The risk-variant SNPs of these genes change the function in …

[PDF][PDF] … the mechanism of interactions among susceptibility genes towards Type 1 Diabetes, Gut Microbiota Along with Environmental factors, specifically early diet …

KK Kaur, GN Allahbadia, M Singh - doi. org/03.2021/1.1005, 2021 - academia.edu
… a greater genetic chances of generation of TID autoimmunity got … that autoimmunity presents
later following an earlier changerisk factors for the emergence of Type1 Diabetesrelated

[HTML][HTML] Associations of breastfeeding with childhood autoimmunity, allergies, and overweight: The Environmental Determinants of Diabetes in the Young (TEDDY) …

S Hummel, A Weiß, E Bonifacio, D Agardh… - The American journal of …, 2021 - Elsevier
… associated with a lower risk of autoimmunity in genetically at-risk children supports results
from … months did not change the findings, suggesting little influence through the modification of …

Environmental Factors in the Development of Diabetes Mellitus

C Formichi, A Trimarchi, C Maccora, L Nigi… - Environmental Alteration …, 2022 - Springer
… fact, environmental exposure and its interaction with genetic … instance by altering the
availability of substrates, modifying, … ones in genetically predisposed individuals to autoimmunity. …

The multifactorial progression from the islet autoimmunity to type 1 diabetes in children

W Bauer, A Gyenesei, A Krętowski - International Journal of Molecular …, 2021 - mdpi.com
… phase suggests that environmental elements change the pace … the genetic, immunological
and environmental risk factors … The gene-environmental interactions exist, and the underlying …

The role of epigenetics in type 1 diabetes

Z Xie, C Chang, G Huang, Z Zhou - … in Allergy and Autoimmunity, 2020 - Springer
… an autoimmune disease caused by the interaction between genetic alterations and environmental
factors… Environmental factors may change the expression of genes through epigenetic …

Autoimmunity-associated polymorphisms and their effects on the immunophenotype: Cohort generation and subject immunophenotyping in the Finnish Diabetes …

L Nygård - 2021 - doria.fi
… homeostasis, alter gene-environment interactions and enable the … environmental factors,
such as viral infections, have been shown to modulate the risk of developing autoimmunity

Food Consumption and Risk of Islet Autoimmunity and Type 1 Diabetes in Children at Increased Genetic Susceptibility for Type 1 Diabetes

SM Virtanen, EJ Peltonen, L Hakola, S Niinistö… - The Journal of …, 2024 - Elsevier
… -associated disease risk, or breastfeeding at 6 months of age modified the association
between food consumption and type 1 diabetes related endpoints, the interaction term between …