KM Sullivan, K Susztak - Nature Reviews Nephrology, 2020 - nature.com
… induces a quantitative change in geneexpression. Therefore, … To identify potential genes involved in chronic kidney … with kidney function that uniquely influenced geneexpression in the …
… of regulatory variants that impact geneexpression, rather than amino acid changes. Data on … Genetic-variation-drivengene-expressionchangeshighlightgenes with importantfunctions …
L Spurr, N Alomran, P Bousounis - Bioinformatics - academia.edu
… tool to uncover genetic variants regulating phenotypic features. QTL methods have been successfully applied to a variety of molecular traits, including geneexpression (eQTL), splicing (…
J Fan, J Hu, C Xue, H Zhang, K Susztak, MP Reilly… - … genetics, 2020 - journals.plos.org
… that impact geneexpression, rather than amino acid changes. Data on geneexpression from … Results from our analysis shed light on the functional roles of GWAS identified genetic …
… changes in splicing do not display a concomitant change in … kidney DNA methylation with geneexpression and alternative … , but many play essential biological roles of yet unknown …
… For the 29 lead genes, we studied geneexpression in kidneys in human transcriptomics … only for 29 genes and two tissues), including fibrosis at first biopsy and change in the mesangial …
Y Yan, H Liu, A Abedini, X Sheng, M Palmer… - Nature …, 2024 - nature.com
… geneexpressionchanges, most notably those playing role in … underlying genetic variation-driven methylation changes may … , we examined geneexpressionchanges driven by …
… Our recent studies indicate that regulatory variants could play a role in modulating gene expressionchanges during development (for example, Uncx and Shroom3) and these genes …
D Mukhi, L Li, H Liu, T Doke… - The Journal of …, 2024 - Am Soc Clin Investig
… : human kidney geneexpression and methylation quantitative … We did not observe a change in the expression of genes … models will be essential to study the role of other genes at this …