The potential effect of aberrant testosterone levels on common diseases: a mendelian randomization study

AAS Syed, L He, Y Shi - Genes, 2020 - mdpi.com
testosterone associations measured in men; therefore, our findings are largely relevant to
common diseases in men. … region to genetically predict testosterone. SHBG can bind to free …

Genetic Variation and Mendelian Randomization Approaches

M Yazdanpanah, N Yazdanpanah… - Nuclear Receptors in …, 2022 - Springer
… on causal effects of genetically predicted estradiol on systemic inflammation among women
genetic predictors of testosterone with CVD and associated risk factors in men using genetic

The role of cortisol in ischemic heart disease, ischemic stroke, type 2 diabetes, and cardiovascular disease risk factors: a bi-directional Mendelian randomization study

MK Kwok, I Kawachi, D Rehkopf, CM Schooling - BMC medicine, 2020 - Springer
… Observationally, higher plasma cortisol to testosterone ratio has been found associated
with … Another MR showed genetically predicted cortisol based on two genetic instruments …

Composite trait Mendelian randomization reveals distinct metabolic and lifestyle consequences of differences in body shape

J Sulc, A Sonrel, N Mounier, C Auwerx… - Communications …, 2021 - nature.com
… While this has improved our understanding of the genetic basis … We also found the negative
effects of PC3 on testosterone … Using the GIANT consortium as a separate sample 25 , we …

Association between metabolic syndrome, hepatic steatosis, and testosterone deficiency: evidences from studies with men and rodents

DAM Hermoso, PFV Bizerra, RP Constantin… - … Aging Male, 2020 - Taylor & Francis
… An important factor that could be behind this intricate relationship is inflammation promoted
… incidence of MetS, it would be expected that testosterone replacement therapy (TRT) would …

[HTML][HTML] Menopause and cardiometabolic diseases: what we (don't) know and why it matters

ZM Roa-Díaz, PF Raguindin, A Bano, JE Laine, T Muka… - Maturitas, 2021 - Elsevier
Mendelian randomization (MR) studies tried to clarify some of the discrepancies. A recent
MR study suggested that genetically predisposed higher testosterone … but genetically-predicted

Genome‐wide association studies: utility and limitations for research in physiology

N Pereira Ciochetti, B Lugli‐Moraes… - The Journal of …, 2023 - Wiley Online Library
genetic correlation between these phenotypes; of the 72 significant signals shared between
total testosterone in men and total testosterone in … found that, in a separate sample of 12 848 …

Environmental risk factors for schizophrenia and bipolar disorder and their relationship to genetic risk: current knowledge and future directions

N Robinson, SE Bergen - Frontiers in genetics, 2021 - frontiersin.org
… These genetic findings related to inflammatory genes are consistent with the possibility
that the … Using Mendelian randomization (MR), they concluded that those with increased …

[PDF][PDF] Uncovering the genetic drivers of cutaneous melanoma and its risk factors

N Ingold - 2024 - eprints.qut.edu.au
men and women. I also show how differentiating nevus morphologies in … in a separate
sample. This indicates that germline … Finally, using Mendelian randomisation, I show that per one …

Spectrophotometric and chromatographic strategies for exploring of the nanostructure pharmaceutical formulations which contains testosterone undecanoate

M Butnariu, I Sarac, I Samfira - Scientific Reports, 2020 - nature.com
… (NPF) which contains testosterone undecanoate (TU) been … In most Pharmacopoeias
testosterone is described as an … high wave-length can be predicted. Maximum absorption occurs …