Association of early childhood caries with bitter taste receptors: A meta-analysis of genome-wide association studies and transcriptome-wide association study

E Orlova, T Dudding, JM Chernus, RN Alotaibi… - Genes, 2022 - mdpi.com
… Although genetics affects early childhood caries (ECC) risk, few studies have focused on
finding its specific genetic determinants. Here, we performed genome-wide association studies (…

Federated principal component analysis for genome-wide association studies

A Hartebrodt, R Nasirigerdeh… - … Conference on Data …, 2021 - ieeexplore.ieee.org
… An attractive application case for FL are genome-wide association studies (GWAS), which
investigate the relationship of genetic variation with phenotypic traits on large cohorts [2], [3]. …

Population size in QTL detection using quantile regression in genome-wide association studies

GF Oliveira, ACC Nascimento, CF Azevedo… - Scientific Reports, 2023 - nature.com
… In this context, genome-wide association studies (GWAS) have been conducted in order to
identify genetic variations that may be associated with phenotypic traits of interest 5,6,7,8,9 . …

[HTML][HTML] … and common risk genes of rheumatoid arthritis associated with three autoimmune diseases based on large-scale cross-trait genome-wide association studies

YP Wen, ZG Yu - Frontiers in Immunology, 2023 - frontiersin.org
… In this paper, a large-scale cross-trait Genome-wide Association Studies (GWAS) was
conducted to investigate the genetic overlap among rheumatoid arthritis, multiple sclerosis, …

Ultra low-coverage whole-genome sequencing as an alternative to genotyping arrays in genome-wide association studies

V Chat, R Ferguson, L Morales, T Kirchhoff - Frontiers in Genetics, 2022 - frontiersin.org
… An array-based genotyping approach has been the standard practice for genome-wide
association studies (GWASs); however, as sequencing costs plummet over the past years, ultra …

Meta-analysis of genome-wide association studies uncovers shared candidate genes across breeds for pig fatness trait

H Zeng, Z Zhong, Z Xu, J Teng, C Wei, Z Chen… - BMC genomics, 2022 - Springer
Background Average backfat thickness (BFT) is a critical complex trait in pig and an important
indicator for fat deposition and lean rate. Usually, genome-wide association study (GWAS) …

Genetics of resilience: Implications from genomewide association studies and candidate genes of the stress response system in posttraumatic stress disorder and …

S Maul, I Giegling, C Fabbri, F Corponi… - American Journal of …, 2020 - Wiley Online Library
… 5 GENOME-WIDE ASSOCIATION STUDIES Genome-wide association studies represent
the methodological answer to the observation of the highly polygenic component of psychiatric …

Integrated multi‐omics analyses and genomewide association studies reveal prime candidate genes of metabolic and vegetative growth variation in canola

D Knoch, RC Meyer, MC Heuermann… - The Plant …, 2024 - Wiley Online Library
genome-wide association studies. We identified genomic regions associated with phenotypic
variation at the early phase of vegetative plant growth and related traits, studied links …

Genomic selection and genomewide association studies in tetraploid chipping potatoes

J Pandey, DC Scheuring, JW Koym… - The Plant …, 2023 - Wiley Online Library
Genome-wide association studies identified quantitative trait loci on chromosome 5 for vine
maturity and chromosomes 1, 3, and 7 for chip color. This research has laid the groundwork …

Leveraging effect size distributions to improve polygenic risk scores derived from summary statistics of genome-wide association studies

S Song, W Jiang, L Hou, H Zhao - PLoS computational biology, 2020 - journals.plos.org
… Calculating polygenic risk score (PRS) has become widely used due to its simplicity and
effectiveness, where only summary statistics from genome-wide association studies are needed …