[HTML][HTML] Genome-wide association studies

E Uffelmann, QQ Huang, NS Munung… - … Reviews Methods …, 2021 - nature.com
… variants between individuals who are ancestrally similar but differ … Now that reliable genetic
associations for various … are increasingly popular and informative, but substantial work is …

[HTML][HTML] An overview of strategies for detecting genotype-phenotype associations across ancestrally diverse populations

I Simonin-Wilmer, P Orozco-del-Pino, DT Bishop… - Frontiers in …, 2021 - frontiersin.org
Genome-wide association studies (GWAS) have been very … of the methods used for the
analysis of admixed populations, we … of the association tests there will be less data to work with, …

[HTML][HTML] Admixed populations improve power for variant discovery and portability in genome-wide association studies

M Lin, DS Park, NA Zaitlen, BM Henn… - Frontiers in genetics, 2021 - frontiersin.org
… from a baseline genome-wide F ST when the ancestral allele … the two populations of ancestral
origin (section “Methods” and … trait studies in diverse populations, especially populations of …

Systematic review of genome-wide association studies of anxiety disorders and neuroticism

K van der Walt, M Campbell, DJ Stein… - The World Journal of …, 2023 - Taylor & Francis
… sizes, more rigorous phenotyping and include more ancestrally diverse population groups.
… collaborative groups collate data for joint analysis) is a powerful method for detecting genetic …

Large-scale genome-wide association study of coronary artery disease in genetically diverse populations

C Tcheandjieu, X Zhu, AT Hilliard, SL Clarke… - Nature medicine, 2022 - nature.com
… of CAD across multiple ancestral groups, identify 95 novel … CAD 7,8 and genome-wide
association studies (GWAS) to … analyses stratified by population and the analytic approach for the …

Improving polygenic prediction in ancestrally diverse populations

Y Ruan, YF Lin, YCA Feng, CY Chen, M Lam, Z Guo… - Nature …, 2022 - nature.com
… cross-population predictive performance. As existing genome-wide association studies (GWAS) …
The use of PRS-CSx, as well as the ‘mult’ methods examined in this work, requires a …

Advances in genome-wide association studies of complex traits in rice

Q Wang, J Tang, B Han, X Huang - Theoretical and Applied Genetics, 2020 - Springer
… a trait in natural populations, are a powerful approach for … seven alleles with different effects
(the ancestral allele; four … especially when different populations and different numbers of …

[PDF][PDF] Evaluating the power and limitations of genome-wide association studies in Caenorhabditis elegans

SJ Widmayer, KS Evans, S Zdraljevic, EC Andersen - G3, 2022 - academic.oup.com
… used a simulation-based approach to provide benchmarks of … populations that are
more representative of the ancestral niche of … in diverse populations. Genome Med. 2014;6(10):91. …

[HTML][HTML] Current affairs of microbial genome-wide association studies: approaches, bottlenecks and analytical pitfalls

JE San, S Baichoo, A Kanzi, Y Moosa… - Frontiers in …, 2020 - frontiersin.org
ancestral recombination events. It is, however, important to note that determining recombination
across a diverse … We recommend more work to be done toward correcting LD both in …

[PDF][PDF] Sequencing-based genome-wide association studies reporting standards

A McMahon, E Lewis, A Buniello, M Cerezo, P Hall… - Cell Genomics, 2021 - cell.com
… publication-level, broad ancestral categories of samples. Mirroring what … methods being
complex. The GWAS Catalog reiterates its stance in encouraging analysis of diverse populations