[HTML][HTML] Genome-wide analysis reveals the association between alternative splicing and DNA methylation across human solid tumors

X Sun, Y Tian, J Wang, Z Sun, Y Zhu - BMC medical genomics, 2020 - Springer
Alternative splicing (AS) is one of the conserved biological processes … Pre-mRNA splicing
is a key step of gene expression in which introns within nascent RNA are removed, and exons

[HTML][HTML] Genome-wide characterization of alternative splicing events and their responses to cold stress in tilapia

BJ Li, ZX Zhu, H Qin, ZN Meng, HR Lin, JH Xia - Frontiers in genetics, 2020 - frontiersin.org
Alternative splicing was an essential mechanism in stress response. In this study, we
characterized the genome-wide AS events in ten different tissues and identified cold tolerant …

Role of alternative splicing in health and diseases

H Sharma, K Yadav, RD Sharma - … and translation in health and disease, 2023 - Elsevier
Genome-wide platforms for assessing AS are a powerful tool … the 5′ end of the pre-mRNA
from degradation by nucleases … events on microarray data (both for exon and junction arrays)…

Computational analyses of non-canonical architectural and structural features associated with alternative splicing

GE Parada Gonzalez - 2021 - repository.cam.ac.uk
… However, nuclear pre-mRNA splicing is carried out by the … of exon-exon junctions, forming
what is known as exon-… that microarrays enabled the first genome-wide assessments …

A genome-wide analysis of the gene expression and alternative splicing events in a whole-body hypoxic preconditioning mouse model

J Li, H Zhao, Y Xing, T Zhao, L Cai, Z Yan - Neurochemical Research, 2021 - Springer
… High-through put microarray analyses have been … -transcriptional processes, such as
pre-mRNA alternative splicing (AS), were … Numbers indicate the exon-exon junction read counts. …

[HTML][HTML] Alternative splicing in normal and pathological human placentas is correlated to genetic variants

CSM Ruano, C Apicella, S Jacques, G Gascoin… - Human Genetics, 2021 - Springer
exon level using exon-microarrays. In parallel, the same patients and controls were genotyped
using SNP-microarray … couples that were significant at a genome-wide threshold (p < 10 –…

[HTML][HTML] Genome-wide profiling of alternative splicing in glioblastoma and their clinical value

Y Li, D Guo - BMC cancer, 2021 - Springer
… machine that removes introns from a transcribed pre-mRNA. … review and database searches,
we found 404 splicing factors … and new splicing variants comparing with microarrays used in …

[HTML][HTML] Alternative splicing: expanding the landscape of cancer biomarkers and therapeutics

C Bessa, P Matos, P Jordan, V Gonçalves - International Journal of …, 2020 - mdpi.com
… of dysregulated splicing signatures on a genome-wide scale and … mechanisms affect alternative
pre-mRNA splicing and … Compared with gene expression microarrays, also designed to …

[HTML][HTML] Genetic risk variants for multiple sclerosis are linked to differences in alternative pre-mRNA splicing

E Putscher, M Hecker, B Fitzner, N Boxberger… - Frontiers in …, 2022 - frontiersin.org
… and of individual exons and exonexon junctions in B cells … SNP according to the genome-wide
association study (GWAS… the ASE of pre-mRNA from HLA-C: first, in the microarray data, …

[HTML][HTML] Genome-wide transcriptional analysis reveals alternative splicing event profiles in hepatocellular carcinoma and their prognostic significance

Y Xiong, G Yang, K Wang, M Riaz, J Xu, Z Lv… - Frontiers in …, 2020 - frontiersin.org
… There is a need for a detailed analysis of alternative splicing (AS) and its underlying biological
and … Percent spliced in (PSI) values and transcriptional splicing patterns of genes were …