… Variation in MS incidence rate according to geographic region is well-described, typically …
to examine trends over time in MS incidence rates, globally and within geographic regions. …

… Importance Racial, ethnic, and geographic differences in multiple sclerosis (MS) are important
… The highest sex ratios (female to male) were noted in the 45- to 54-year-old age group for …

… processes or through behavioral differences. In this review, we explore these differences
further and … in sex ratios across latitudes (110). UVR exposure may influence the production of …

… , a z-score test was used to compare the sex ratios. The one-sided z-test with a level of … of
sex ratios between the two studies to investigate the direction of change in sex ratio over time. …

… regarding temporal, geographical and demographic alterations in … showed an increasing
trend in incidence rate in some … Overall the sex ratio was stable over the period, in contrast to …

… same geographic area, we considered both periods. This has enabled us to assess time-trend …
It remains to be determined whether these differences in sex distribution are genuine in …

… in MS occurrence and the remarkable geographical variations … It should be noted that the
trend of sex ratio in the present … The obtained trend in the current study using the extracted …

… F/M ratio in MS patients was 1.2. Interestingly, clear regional differences were seen in this
gender ratio already in the … A clear trend of increasing MS prevalence was observed through …

… changes in the epidemiology of MS, focusing on trends in the incidence of the disease over
time and trends in … in the sex ratio 16 . In some studies that showed an overall increase in the …

… to determine the incidence of this disease over the past eleven years in … rate as the number
of new cases in 100,000 average population of the region in a year. The trend of the changes …