[PDF][PDF] Hallmarks of environmental insults

A Peters, TS Nawrot, AA Baccarelli - Cell, 2021 - cell.com
… In summary, epigenetics is a prime hallmark of environmental insults, and persuasive evidence
exists that environmental exposures cause alterations in gene regulation via alteration in …

Mitochondrial dysfunction as a hallmark of environmental injury

C Duarte-Hospital, A Tête, F Brial, L Benoit, M Koual… - Cells, 2021 - mdpi.com
… by an exposure to environmental pollutants are extremely … as a major hallmark of environmental
insults. Here, we present … , whose activation by environmental pollutants leads to various …

[PDF][PDF] Hallmarks of health

C López-Otín, G Kroemer - Cell, 2021 - cell.com
… 1: Integrity of Barriers All living beings must shield from their environment by erecting …
Alterations in this communication axis—associated with gene polymorphisms, environmental insults

Impacts of environmental insults on cardiovascular aging

Y Lan, S Wu - Current Environmental Health Reports, 2022 - Springer
… of environmental influences on cardiovascular aging, by summarizing epidemiological and
mechanistic evidence for the cardiovascular health impact of major environmental stressors, …

Transgenerational effects of early environmental insults on aging and disease incidence

M Ambeskovic, TJ Roseboom, GAS Metz - Neuroscience & Biobehavioral …, 2020 - Elsevier
… Prenatal or early postnatal exposure to stress, undernutrition or environmental toxicants
may … Second, we discuss experimental and clinical findings linking early environmental

[HTML][HTML] The missing hallmark of health: psychosocial adaptation

C López-Otín, G Kroemer - Cell Stress, 2024 - ncbi.nlm.nih.gov
… The gut vascular barrier protects from external insults through a multilayered structure that
… Circadian misalignment of environmental cues with the endogenous clock program due to …

Hallmarks of cancer—the new testament

SS Senga, RP Grose - Open biology, 2021 - royalsocietypublishing.org
… between cancer and the environment, showing deposits of … birth, establish a favourable
anaerobic environment in the gut … The two motifs were described to be from mutagenic insult

Embracing cancer complexity: Hallmarks of systemic disease

C Swanton, E Bernard, C Abbosh, F André, J Auwerx… - Cell, 2024 - cell.com
… carcinogenesis, synthesized as the hallmarks of cancer. Despite … and how multifaceted
environmental and physiological … and unravel gene-environment interactions, providing a modern …

Hallmarks of aging in macrophages: consequences to skin inflammaging

GR Guimarães, PP Almeida, L de Oliveira Santos… - Cells, 2021 - mdpi.com
… Its aging reflects both intrinsic and extrinsic processes resulting from the constant insults it is
environmental factors, such as UV radiation, genomic instability could be a central hallmark

Hallmarks of cancer: new dimensions

D Hanahan - Cancer discovery, 2022 - AACR
… More-over, senescent fibroblasts in normal tissues produced in part by natural aging or
environmental insults have similarly been implicated in remodeling tissue microenvironments via …