… ) and thus to analyse the extent of HCMVgenomediversity and its potential impact on clinical … Similarly, extensiveHCMV strain variability among different individuals with high intrahost …
OJ Charles, C Venturini, S Gantt… - Proceedings of the …, 2023 - National Acad Sciences
… We highlight examples of where our approach can help to provide insights for further … To characterize CMVgenomicdiversity, we first aligned the genomes and then calculated …
NM Suárez, E Blyth, K Li, T Ganzenmueller… - Frontiers in cellular …, 2020 - frontiersin.org
… , we applied high-throughput sequencing coupled with HCMV-… These findings highlight the importance of monitoring … present at low level may become prevalent at later stages due to …
… on the functional effect of HCMVgeneticdiversity and we define … Extensiveanalysis of antibody responses indicated that … changes in genomic regions, thus highlighting the presence of …
… Humancytomegalovirus (HCMV) is an important opportunistic … More recently, the development of high–throughput … is highly prevalent [18], the first four complete HCMVgenome …
S Camiolo, NM Suarez, A Chalka, C Venturini… - Virus …, 2021 - academic.oup.com
… HCMVgenomics has been significantly advanced in recent years by high-throughput … variation among HCMV strains, had previously required extensive manual intervention. The variant …
S Camiolo, J Hughes, F Baldanti, M Furione… - Virus …, 2022 - academic.oup.com
… in high-throughput sequencing. However, the underlying … on the basis of extensive experimentation. The effects on read … be drawn about the intrahost geneticdiversity of viruses. In …
SA Ross, P Pati, TL Jensen, JB Goll… - The Journal of …, 2020 - academic.oup.com
… Because CMV has a large genome with extensive variability within many gene regions and only a limited number of clones were sequenced to determine genotypes of gN, US28, and …
… In this review, we describe new technologies and provide guidelines for the high-throughput sequencing and genetic and evolutionary analyses of viral populations and metaviromes, …