8 Oxidative stress and antioxidants in nutrition

V Valls-Bellés - degruyter.com
… It has an important role as an antioxidant in the cellular defense against free radicals, being
able … do nutritional antioxidants really work: Nucleophilic tone and para-hormesis versus free

The underexplored dimensions of nutritional hormesis

S Pande, S Raisuddin - Current Nutrition Reports, 2022 - Springer
… mechanism of natural antioxidants (except Vitamin E) from free radical scavenging to …
that maintains nucleophiles and brings about desirable health benefits of antioxidants. Our …

Reconceptualization of hormetic responses in the frame of redox toxicology

Z Skaperda, F Tekos, P Vardakas, C Nepka… - International Journal of …, 2021 - mdpi.com
antioxidant properties can confine the pernicious outcomes of chemical compounds by
interrupting the propagation of free … , in contrast with the dietary supplements, did not possess the …

Antioxidant phytochemicals in cancer prevention and therapy—An update

A Wall-Medrano, FJ Olivas-Aguirre - Functional Foods in Cancer …, 2020 - Elsevier
free radical theory of cancer has been challenged by the nucleophilic tone and para-hormesis
to reduce this burden are yet to be seen, but public health systems should be prepared for …

[HTML][HTML] Unraveling the parahormetic mechanism underlying the health-protecting effects of grapeseed procyanidins

G Baron, A Altomare, L Della Vedova, F Gado… - Redox Biology, 2024 - Elsevier
… with the concept of para-hormesis, ultimately orchestrating … view phenolic antioxidants,
seeing them not just as free radical … ultimately leads to the restoration of nucleophilic tone [55]. In …

Expected and unexpected effects of pharmacological antioxidants

I Tyuryaeva, O Lyublinskaya - International Journal of Molecular Sciences, 2023 - mdpi.com
… diseases are the result of the damaging effects of free … The idea of using pharmacological
antioxidants for health … , and maintain so-called nucleophilic tone [16] in cells, granting …

[PDF][PDF] Redox homeostasis in Alzheimer's disease Jan Homolak1, 2

J Homolak - researchgate.net
… systems (eg cysteine), and iii) stimulating nucleophilic tone by parahormetic activation of the
Do Nutritional Antioxidants Really Work: Nucleophilic Tone and Para-Hormesis Versus Free

Antioxidant pharmacology

VK Koltover, TA Skipa - Anti-Aging Pharmacology, 2023 - Elsevier
… As a matter of fact, this book spurred studies on free radicals and antioxidant therapy for … ,”
to the idea that microbiota regulates body health and longevity, the idea which had been firstly …

Science and claims of the arena of food bioactives: comparison of drugs, nutrients, supplements, and nutraceuticals

F Visioli - Food & Function, 2022 - pubs.rsc.org
nucleophilic (antioxidant) response. Such compounds generally have antibacterial and/or
antiviral activities, are pesticides, and are … , in turn, increases the nucleophilic tone. The latter …

Redox homeostasis in Alzheimer's disease

J Homolak - Redox signaling and biomarkers in ageing, 2022 - Springer
… regulating the electrophilic and nucleophilic tone of the cell/… derivatives can be generated
either by non-enzymatic free … to act as chemical antioxidants are now suggested to exert …