BloodBrain Barrier Dysfunction and Exposure to Head Impacts in University Football Players

CMA Jones, L Kamintsky, E Parker… - Clinical journal of …, 2024 - journals.lww.com
Image acquisition was performed as previously described. In brief, the acquisition protocol
… in American football. Using DCE-MRI scanning, we found that football players had …

Slow blood-to-brain transport underlies enduring barrier dysfunction in American football players

R Veksler, U Vazana, Y Serlin, O Prager, J Ofer… - Brain, 2020 - academic.oup.com
… role for microvascular injury, specifically bloodbrain barrier dysfunction. Thus, our main …
rmTBI in amateur American football players. For the first time, using human brain imaging, we …

Dynamic bloodbrain barrier regulation in mild traumatic brain injury

E O'Keeffe, E Kelly, Y Liu, C Giordano… - Journal of …, 2020 - liebertpub.com
… , that bloodbrain barrier (BBB) dysfunction is associated … head kinematics in American
football games. The linear … post-match) underwent a scan within 2 h of playing a full contact …

[PDF][PDF] Blood-brain barrier response in the context of sports-related TBI

E O'Keeffe - 2020 - tara.tcd.ie
… in neuroanatomical structure via diffusion tensor imaging (DTI). … and professional American
football players suggested that … a degree of blood brain barrier dysfunction (BBBD), both in …

Peripheral blood and salivary biomarkers of bloodbrain barrier permeability and neuronal damage: clinical and applied concepts

D Janigro, DM Bailey, S Lehmann, J Badaut… - Frontiers in …, 2021 - frontiersin.org
… immediately after football games as compared to pregame baselines in players experiencing
… using diffusion tensor imaging were correlated to astrocyte dysfunction and astrogliosis at …

Quantitative imaging of blood-brain barrier permeability following repetitive mild head impacts

J Leaston, J Qiao, IC Harding, P Kulkarni… - Frontiers in …, 2021 - frontiersin.org
… Failure in the blood brain barrier (BBB) lies at the foundation of cerebrovascular dysfunction
… Athletes playing American football and thought to have mild, sub-concussive head injuries …

Blood and MRI biomarkers of mild traumatic brain injury in non-concussed collegiate football players

E Cho, J Granger, B Theall, N Lemoine, D Calvert… - Scientific reports, 2024 - nature.com
… and the brain imaging outcomes, we characterized the correlations between BDNF, S100B,
… head and subsequent disruption of the bloodbrain barrier, without being associated with …

Permeability of the bloodbrain barrier after traumatic brain injury: radiological considerations

M Amoo, PJ O'Halloran, J Henry… - Journal of …, 2022 - liebertpub.com
impairment visible on DTI in a cohort of American football … across membranes, permeability
imaging generally depends on … of training in 40% of football players versus only 8.3% of …

Bloodbrain barrier disruption and ventricular enlargement are the earliest neuropathological changes in rats with repeated sub-concussive impacts over 2 weeks

B Hiles-Murison, AP Lavender, MJ Hackett… - Scientific Reports, 2021 - nature.com
… The sub-concussive rats also presented significant BBB dysfunction in the cerebral cortex
and … Representative immunomicroscopy images are presented on the right with IgG shown in …

Quantitative water permeability mapping of blood-brain-barrier dysfunction in aging

JN Ford, Q Zhang, EM Sweeney, AE Merkler… - Frontiers in Aging …, 2022 - frontiersin.org
… An emerging technique to image BBB water exchange rate (k W ) is diffusion-weighted … )
based DW-ASL approaches for in vivo imaging suffer from low spatial resolution, limited brain …