A bacterium from the human microbiota as a vaccine vector. Efficient priming of the murine immune system by vaginal delivery of recombinant Streptococcus gordonii

B Philosof - 2022 - usiena-air.unisi.it
… induced by a recombinant Streptococcus gordonii vaccine vector expressing a heterologous
antigen … gordonii expressing the multivalent MOMP antigen of C. trachomatis, CTH522, was …

Tetanus toxin fragment C: structure, drug discovery research and production

C Bayart, A Mularoni, N Hemmani, S Kerachni, J Jose… - Pharmaceuticals, 2022 - mdpi.com
… antigen present in the current vaccine (tetanus toxoid, TTd) [69,… vaccines against TT, ie, they
served both as an expression … cholerae O1 Inaba and recombinant fragment of tetanus toxin

[HTML][HTML] Recombinant production of a novel fusion protein: listeriolysin O fragment fused to S1 subunit of pertussis toxin

H Forghani, MJ Makiani, HZ Jaliani… - Iranian Biomedical …, 2021 - ncbi.nlm.nih.gov
… by aP vaccines compared with the wP vaccines or natural … mL -1 of ampicillin at 37 C
and 28 C, respectively, induced … Expression of the recombinant proteins PTS1 and LLO-PTS1 …

Mucosal immunization against pertussis: lessons from the past and perspectives

V Dubois, C Locht - Frontiers in Immunology, 2021 - frontiersin.org
… Augmenting the expression of PRN by the use of a strong … S1 subunit and tetanus toxin
fragment C produced detectable … parenteral immunization with crude extracts of the recombinant S…

Discovery and engineering of the antibody response against a prominent skin commensal

DA Bousbaine, K Bauman, YE Chen, V Yu, P Lalgudi… - bioRxiv, 2024 - biorxiv.org
… domain of Aap is replaced by tetanus toxin fragment 42 C, we elicit a potent neutralizing …
Immunization with recombinant Streptococcus gordonii expressing tetanus 502 toxin fragment C

Immune modulatory capacity of probiotic lactic acid bacteria and applications in vaccine development

N Mojgani, Y Shahali, M Dadar - Beneficial microbes, 2020 - wageningenacademic.com
… fed infants, the tetanus toxoid antigen induced lower amounts of … with recombinant
Streptococcus gordonii expressing E7 or … for the recombinant C-terminanal 19-kU fragment

Listeria delivers tetanus toxoid protein to pancreatic tumors and induces cancer cell death in mice

…, X Zhang, K Lin, C Gravekamp - Science translational …, 2022 - science.org
expressed, weak tumor–associated antigens (28). In our approach, Listeria is used to deliver
strong childhood vaccine … TT 856-1313 , a nontoxic fragment of the C terminus of TT cDNA (…

The bacterial spore as a mucosal vaccine delivery system

A Saggese, L Baccigalupi, G Donadio, E Ricca… - International Journal of …, 2023 - mdpi.com
… spore by either recombinant or non-recombinant approaches, … spore expressing the C
fragment of the tetanus toxin on its … gordonii [118], LTB is displayed as a monomer, while LTB …

Recent development of oral vaccines

Y Liu, DMK Lam, M Luan… - Experimental and …, 2024 - spandidos-publications.com
Recombinant vaccines against HBsAg (92), tetanus toxin (93), diphtheria … administration
of the vaccine in mice (118). However, the expression of non-toxic C fragment protein on the …

Probiotics and probiotic-based vaccines: A novel approach for improving vaccine efficacy

N Kazemifard, A Dehkohneh… - Frontiers in …, 2022 - frontiersin.org
… Another study on infants receiving BCG, OPV, tetanus toxoid (… be efficiently expressed on
the surface of recombinant L. … -1ß (IL-1ß) or expressed the surface flagellin subunit C (FliC) as …