… in the adaptive immune system would explain all that we observe in aging from the … innate
immune response should not be modulated by what we are now calling the immunobiography. …

… complex and heterogeneous … emphasis during the COVID-19 pandemic, bringing to the
fore the critical need to combat immunosenescence and improve older people's immune function …

… of the immune system changes with aging and how this … we refer to as lifelong
immunobiography and envirobiography (… to the heterogeneous impact of aging on the immune …

… by proposing the new concept of “immunobiography”, defined as the combination of type,
dose, … the large heterogeneity of immunological responses observed in the elderly (35). …

… aging has been termed “inflammaging”. This review will focus on age-related changes in the
immune system … the dynamics of aging, and the complexities and heterogeneity in regards …

… in determining the “immunobiography” of the individual. This … has been hypothesized that
the inflammaging process is not … the contribution of immune system aging to organism aging a …

… the innate immune system in inflammaging, senescence, and aging … “immunobiography”
[36]. This phenomenon shapes the … are highly heterogeneous and contribute to inflammaging at …

… to the immunobiography. Furthermore, the contribution of the … the immune changes with
aging and how the immune system … immune system with aging combined with the inflammaging …

… the immune response and the combination of type 2 inflammation and inflammaging in asthma
in the elderly … Along with aging, heterogeneous microbiota, due to increasing pathobionts …

… even more to the immune system (immunobiography). Finally, the … heterogeneity of
immunological responses, especially in … inflamm-aging is only minimally linked to the immune …