Z Wu, M Nicoll, RJ Ingham - Experimental hematology & oncology, 2021 - Springer
… of some AP-1 proteins in cHL and ALK+ ALCL. Forced expression of dominantnegative A-… sensitive to staurosporine and doxorubicin-induced apoptosis [110]. This suggests that GzB …
P Xue, W Fan, Z Diao, Y Li, C Kong, X Dai, Y Peng… - Molecular …, 2020 - Elsevier
… of AP-1) and NF-κB activity after … induced PTEN expression is dependent on AP-1 and NF-κB in trophoblasts, suggesting that AP-1 and NF-κB are positive regulators of PTEN expression…
… Specifically, we showed that BM-inducedexpression of JunB was significantly … -expressed negative regulator of bone formation. Consequently, downregulation of Fra-1, Fra-2 and c-Jun …
D Song, Y Lian, L Zhang - Frontiers in Immunology, 2023 - frontiersin.org
… with c-Jun increases c-Fos nuclear retention inhibits nuclear exit, … AP-1 and NF-κB dual inhibitor SP100030 is one of the first reported small molecules to inhibit gene expressioninduced …
F He, S Luo, S Liu, S Wan, J Li, J Chen, H Zuo… - Journal of …, 2022 - Elsevier
… the phosphorylation level of c-JUN. Thus, the inhibitory … genes were potentially via targeting c-JUN/AP-1, instead of c-FOS, to suppress phosphorylation and subsequently downregulate …
QC Zhu, S Li, LX Yuan, RA Chen, DX Liu… - International Journal of …, 2021 - mdpi.com
… , a rationally designed small molecule that inhibits the DNA binding activity of cFOS/cJUN, would be of help in exploring … The dominantnegative (DN) trans-activation mutant TAM-67 of …
S Yadav, M Singh, SN Singh, B Kumar - Cell Stress and Chaperones, 2020 - Springer
… hypoxia-induced oxidative stress by modulating the expression of AP-… of AP-1 heterodimer and their regulatedgenes. Our data revealed the role of pc-jun/c-fos, pc-jun/fosB, junD/c-fos, …
… The observation that expression of siRNA-JNK-1 strongly inhibits PMA and PDGF effect in … activity of JNK-1 (probably by blocking the phosphorylation of cJun) and the induction of AP-1 …
P Wan, S Zhang, Z Ruan, X Liu, G Yang, Y Jia, Y Li… - Virulence, 2022 - Taylor & Francis
… c-Jun decreases pro-IL-1β mRNA and inhibits NLRP3 inflammasome activation upon IAV infection. Overall, the findings uncover that AP-1 … mature Caspase-1 protein induced by H3N2 …