[HTML][HTML] Time moderates the interplay between 5-HTTLPR and stress on depression risk: gene x environment interaction as a dynamic process

C Delli Colli, M Borgi, S Poggini, F Chiarotti… - Translational …, 2022 - nature.com
… when investigating the moderating effect of the duration of the stress, if any … effects for both
chronic and acute stress, the effect of the stress closer in time to the assessment of depression

[HTML][HTML] Associations of the serotonin transporter gene polymorphism, 5-HTTLPR, and adverse life events with late life depression in the elderly Lithuanian population

S Simonyte, I Grabauskyte, J Macijauskiene… - Scientific Reports, 2023 - nature.com
polymorphism in the promoter region of the serotonin transporter (5-HTT) encoding gene
(… 5-HTT is a main regulator of serotonergic neurotransmission and is a target of the widely …

… of negative life events on college students' depression: the mediating role of internet addiction and the moderating role of 5-HTT1A gene rs6449693 polymorphism

Z Zeng, Y Hu, L Peng, L Zhan, S Liu, X Ouyang… - Current …, 2023 - Springer
… to influence depression? The current study also proposed hypothesis H3: 5-HTR1A gene
rs6449693 polymorphism plays a moderation role in … between negative events and depression. …

Influence of psychosocial stress on activation in human brain regions: moderation by the 5-HTTLPR genetic locus

X Sun, C Li, X Zhong, D Dong, Q Ming, Y Gao… - Physiology & …, 2020 - Elsevier
… functioning of the 5-HTT gene and lower reuptake efficiency … depression following stressful
life events, and gene-environment interactions have been linked with the onset of depression, …

[HTML][HTML] COMT but Not 5HTTLPR gene is associated with depression in first-episode psychosis: The role of stressful life events

S Tosato, C Bonetto, K De Santi, A Lasalvia… - Genes, 2023 - mdpi.com
… In addition, as previously conducted [11,36], the clustered phased haplotypes frequencies
were estimated, transforming the classification into a triallelic model according to the 5-HTT

[HTML][HTML] Genetic and epigenetic consequence of early-life social stress on depression: role of serotonin-associated genes

T Soga, CH Teo, I Parhar - Frontiers in genetics, 2021 - frontiersin.org
… of a functional polymorphism in the 5-HTT gene in individuals … greater susceptibility to life
stress history for predicting depression, … The influence of epigenetics on 5-HTT is also well …

Work stress and general trust: The mediating effect of depression and the moderating effect of the OXTR gene rs53576

X Yu, Y Dong, Z Li, Y Fang, S Wu, C Wang… - Journal of Affective …, 2020 - Elsevier
gene and work stress could influence general trust jointly. The OXTR gene might moderate
the relationship between work stress … that the OXTR gene could moderate the relationship …

Stress sensitization to depression following childhood adversity: Moderation by HPA axis and serotonergic multilocus profile scores

LR Starr, CB Stroud, ZA Shaw… - Development and …, 2021 - cambridge.org
… As an alternative interpretation to this effect, we examined whether the genetic moderation
Influence of life stress on depression: Moderation by a polymorphism in the 5-HTT gene. …

[HTML][HTML] Examination of associations between personality traits, and polymorphisms of MAO‑A and 5HTT with the severity of menopausal symptoms and depression …

S Esmaeilzadeh, MA Delavar, H Nouri… - Biomedical …, 2020 - spandidos-publications.com
… and depression, as well as between the allele frequency of polymorphisms in the 5-HT
transporter (5-HTT) gene … of a 44-bp 5-HTT-LPR polymorphism was significantly more frequently …

[HTML][HTML] Factors related to age at depression onset: the role of SLC6A4 methylation, sex, exposure to stressful life events and personality in a sample of inpatients …

S Sanwald, K Widenhorn-Müller… - BMC psychiatry, 2021 - Springer
… in search for genetic markers of depression risk. The serotonin transporter (5-HTT) is one
of the most investigated parameters of the 5-HT system in depression research [25, 26]. …