… In this review, we focus on data integrative bioinformatics methods that combine GWAS
with … two types of data integrative methods. First, we describe fine-mapping methods. Fine-…

… Transcriptome-wide association study (TWAS) is an instrumental post-analysis to detect
significant gene-trait associations focusing on modeling transcription-level regulations, which …

… based association scan between trait and predicted transcript level. Such an approach is
known as a transcriptome-wide association … datasets are large-scale proteome studies applying …

… Many integrative genomics approaches have been recently … these integrative methods,
transcriptome-wide association study (TWAS) has become one of the most popular approaches (3…

… Using the final suite of 5,407 MOSTWAS models, we also conducted a transcriptome-wide
association study for risk of major depressive disorder (MDD) using summary statistics from …

… As a result of recent expansions in the large-scale joint genotyping and phenotyping of …
prevailing types of integrative genetic analyses: transcriptome-wide association studies (TWASs) …

… Transcriptome-wide association studies (TWAS) have been recently … approach yielded a
well-controlled Type I error rate while achieving higher power and AUC than competing methods…

… Because of consent and privacy concerns, as well as logistic limitations ( eg., large-scale …
from large-scale association studies. Indeed, using summary statistics across multiple studies …

… The aim of transcriptome-wide association studies (TWAS) is … large-scale genetic association
results from existing studies … methods traditionally used to perform these TWAS studies do …

… Analyzing complex-trait GWAS data We apply INTACT to the large-scale GWAS data of
four complex traits: high-density lipoprotein (HDL) from the GLGC consortium, low-density …