… At present, hairs, nails, and urine are effective biomarkers of arsenic exposure detection …
as a biomarker for arsenic toxicity in the future. Since, the increase in level of arsenic is directly …

… to the interaction between melanocytes and keratinocytes. … biomarker for early detection
and/or therapeutic target for … -induced skin lesions may potentially provide invaluable insight into …

… biomarkers for health effects related to arsenic exposure and … who attributed it to destruction
of melanocytes in the later … significant apoptotic and dyskeratotic keratinocytes. Most of non-…

… analyses of a set of metabolites or certain biomarkers and is often hypothesis-driven. The …
changes in keratinocytes, three studies in fibroblasts, one study examined melanocytes and …

… , study design (model, exposure, biomarkers, pollutants) and … keratinocytes were also
considered. Co-culture models associating fibroblasts/keratinocytes or keratinocytes/melanocytes …

… driven by sustained DNA damage in keratinocytes, melanocytes, and epithelial cells, among
… Extrinsic factors such as excessive sun exposure lead to the skin appearing thick, rough, …

… by mutations that melanocytes acquire in malignancy to … keratinocyte cells were used in
this study for analytical purposes. For clarification, our study did not focus on the UV exposure …

… melanocytes reside among the basal keratinocytes in an … some of the major early insights
that came from extensive classic … of the observations that the biomarkers widely used to define …

… insights into study design, selection of appropriate test system, type of toxicant, route and
length of exposure, and human exposure … of the melanocytes to the surrounding keratinocytes …

… is transported out of melanocytes via melanosomes to surrounding keratinocytes, forming …
these tissues may give further insight into the systemic effects of As exposure. One proposed in …