EE Pearce, R Alsaggaf, S Katta, C Dagnall, G Aubert… - Geroscience, 2022 - Springer
… Telomerelength (TL) and DNAmethylation–based epigenetic … Correlations between leukocyte telomerelength (TL) and … Tcells, and longer in naive enriched Tcells and B cells [29, 30]. …
… age. Similarly, we observed that leukocytetelomerelength decreased with chronological age in our … a positive association between mtDNAcn and leukocytetelomerelength in our cross-…
… Like telomeres, blood DNAmethylation differs by leukocyte … leukocytetelomerelength (rLTL) 4 and genome-wide DNA … , 6 we used the age-telomerelength relationship to study the …
… of age-related DNAmethylation changes is conceivably a promising way towards enhancing our understanding of the molecular mechanisms of ageing [11, 12]. While the bulk of the …
… associated with decreased telomerelength of T-cells (effect … previously found to affect leukocytetelomerelength; however, … smoking and age with DNAmethylation levels available for …
VM Vetter, D Spira, VL Banszerus… - The Journals of …, 2020 - academic.oup.com
… aging, measured by both this new and the established biomarker of aging, relative leukocyte telomerelength (… DNAmethylationage (DNAm age, epigenetic clock) is highly associated …
A Vaiserman, D Krasnienkov - Frontiers in genetics, 2021 - frontiersin.org
… Leukocytetelomerelength vs. … biological age measure such as DNAmethylation-based epigenetic clock [… less naïve CD8+ Tcells and more memory CD8+ Tcells may display relatively …
EE Pearce, S Horvath, S Katta, C Dagnall… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
… DNAmethylation regulates gene expression and has been associated with both … age and telomere shortening [19–21]. A new method utilizing whole genome DNAmethylation array …
… Cord blood leukocytetelomerelength was measured using … age by DNAmethylation biomarkers, ie, Horvath's DNAmethylationage and the Knight's predictor of gestational age. …