DNA methylation-based age prediction and telomere length reveal an accelerated aging in induced sputum cells compared to blood leukocytes: a pilot study in COPD …

M Campisi, F Liviero, P Maestrelli, G Guarnieri… - Frontiers in …, 2021 - frontiersin.org
… Biological aging was assessed in 18 COPD patients (72.4 ± 7.7 years; 50… aging pathways,
using telomere length (TL) and DNA methylation-based age prediction (DNAmAge) and age

Telomere length and epigenetic clocks as markers of cellular aging: a comparative study

EE Pearce, R Alsaggaf, S Katta, C Dagnall, G Aubert… - Geroscience, 2022 - Springer
Telomere length (TL) and DNA methylation–based epigenetic … Correlations between leukocyte
telomere length (TL) and … T cells, and longer in naive enriched T cells and B cells [29, 30]. …

[HTML][HTML] … in older individuals: an analysis of DNA methylation age metrics, leukocyte telomere length, and mitochondrial DNA copy number in the VA normative aging …

J Dolcini, H Wu, JC Nwanaji-Enwerem… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
age. Similarly, we observed that leukocyte telomere length decreased with chronological age
in our … a positive association between mtDNAcn and leukocyte telomere length in our cross-…

The role of blood cell composition in epidemiologic studies of telomeres

JK Kresovich, CG Parks, DP Sandler… - …, 2020 - journals.lww.com
… Like telomeres, blood DNA methylation differs by leukocyteleukocyte telomere length (rLTL)
4 and genome-wide DNA … , 6 we used the age-telomere length relationship to study the …

Ageing affects subtelomeric DNA methylation in blood cells from a large European population enrolled in the MARK-AGE study

…, M Moreno-Villanueva, MET Dollé, E Jansen, T Grune… - GeroScience, 2021 - Springer
… of age-related DNA methylation changes is conceivably a promising way towards enhancing
our understanding of the molecular mechanisms of ageing [11, 12]. While the bulk of the …

Genetic, parental and lifestyle factors influence telomere length

…, S Henkelman, DV Zhernakova, T Sinha… - Communications …, 2022 - nature.com
… associated with decreased telomere length of T-cells (effect … previously found to affect
leukocyte telomere length; however, … smoking and age with DNA methylation levels available for …

Epigenetic clock and leukocyte telomere length are associated with vitamin D status but not with functional assessments and frailty in the Berlin aging study II

VM Vetter, D Spira, VL Banszerus… - The Journals of …, 2020 - academic.oup.com
aging, measured by both this new and the established biomarker of aging, relative leukocyte
telomere length (… DNA methylation age (DNAm age, epigenetic clock) is highly associated …

Telomere length as a marker of biological age: state-of-the-art, open issues, and future perspectives

A Vaiserman, D Krasnienkov - Frontiers in genetics, 2021 - frontiersin.org
Leukocyte telomere length vs. … biological age measure such as DNA methylation-based
epigenetic clock [… less naïve CD8+ T cells and more memory CD8+ T cells may display relatively …

[HTML][HTML] DNA-methylation-based telomere length estimator: comparisons with measurements from flow FISH and qPCR

EE Pearce, S Horvath, S Katta, C Dagnall… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
DNA methylation regulates gene expression and has been associated with both … age and
telomere shortening [19–21]. A new method utilizing whole genome DNA methylation array …

Prenatal lead exposure, telomere length in cord blood, and DNA methylation age in the PROGRESS prenatal cohort

JF Herrera-Moreno, G Estrada-Gutierrez, H Wu… - Environmental …, 2022 - Elsevier
… Cord blood leukocyte telomere length was measured using … age by DNA methylation
biomarkers, ie, Horvath's DNA methylation age and the Knight's predictor of gestational age. …