… In conclusion, I discovered that DR differentially affects lifespan and health span depending
on … the underlying mechanism of DRmediated lifespan and health span extension with the …

… , be detected in short experiments involving longitudinal dFI measurements in just over a few
… with the earlier reported life-long pro-longevity effects of transient rapamycin treatments 37 . …

… , will improve our understanding of the genetics linking life expectancy and healthspan. …
elegans 69 , offering additional life-extending mechanisms through which calcium channel …

… in the long-lived rodent genus Fukomys. To investigate the molecular mechanisms underlying
… stress axis play a key role regarding the extended life expectancy of reproductive vs. non-…

… the genetic signals of extended lifespan may be maintained by … The mechanisms of adaptation
in long-lived animals are … recent progress in comparative biology of long-lived animals, …

… , which were seen in the transcriptomic analysis of Rragc S74N/+ mice (Extended Data
Fig. 2d), are observed in samples from naturally aged CNIO and NIA cohorts (Fig. 3b–d and …

… Recent studies revealed that long-lived mammalian species are … Bats showed a unique,
age-related pattern of gene … can lead to an increase in their health span [78]. They also express …

… Disease-specific prevention and early diagnosis strategies, cornerstones of modern
medicine, contribute to longer life expectancy but only marginally extend health span 2,3 . A …

… available molecular evidence from long-lived biological models. Attesting to the added value
of this approach, the longest-lived mammals are revealing peculiar regulation of autophagy-…

… events in epidemiological and longitudinal clinical studies. The … As long as the repair,
resolution and recovery mechanisms … are endowed with the basic mechanisms that allow them to …