… , controls gene transcription networks to coordinate GC … GC proliferation and not elevated
apoptosis or senescence. Thus… Mice doubly deficient for the Polycomb Group genes Mel18 and …

… Here, we report that the polycomb group-related mammalian … -related mammalian gene,
encodes a transcriptional … Deregulated Mel18 expression can increase cancer cell proliferation …

… driven senescent cells to re-enter the cell cycle through conditional knockdown of proteins
… In turn, depletion of PANDA in senescent cells allows for NF-YA to facilitate transcription of …

… The Polycomb group (PcG) of proteins are transcriptional … in mice deficient in Cbx2 75 or
Mel-18 (Pcgf2). Additionally, … the regulation of proliferation, cell cycle, and senescence of mature …

… The polycomb group (PcG) is a class of highly conserved … Mel-18 protein is a member of the
PcG family that possesses … in cell cycle progression and regulates cell viability via both p53-…

… Polycomb group (PcG) proteins are a group of widely studied … cell proliferation and driving
cellular senescence (Figure 4A) [236]. Meanwhile, MEL-18 also negatively regulated the …

… , senescence is described as a state of irreversible cell cycle arrest, during which cells
are … -promoting genes, including E2F transcription factor target genes such as cyclin A (CcnA), …

… The polycomb group (PcG) proteins are a class of transcriptional repressors that mediate gene
silencing through … of the cell cycle, senescence, DNA damage, and stem cell biology [17]. …

… transcription of developmental genes involved in a wide range of highly dynamic biological
processes such as differentiation, stem cell plasticity or cell cycle … known as MEL-18 or BMI-1)…

… Polycomb group (PcG) proteins are major epigenetic … differentiation is transcriptionally
regulated at two main … ASC cannot proliferate due to their inability to suppress cell cycle inhibitors […