… OATP in 1994 as a candidate for the liver multi- specific organic anion transporter [1], the
OATPs … showed that OATP1B1 and OATP2B1 are similarly expressed in liver throughout the …

… OATP-B and was shown to be ubiquitously expressed, with highest mRNA levels in fetal and
adult liver… the presence of OATP2B1 in the liver and specifically in the sinusoidal membrane …

… of organic anion transport proteins (OATPs) and the Na+-taurocholate transporting polypeptide
… In the present study, transporter protein expression was determined in liver samples from …

… In this review, we use the expression “acute DDI” when the changes in transport or … , and
the inhibition of OATPs such as OATP1B1 and OATP1B3 in the liver. All those situations induce …

… mechanisms affecting membrane transporter expression and function. These … hepatic
OCTs, OATPs and OATs and discuss recent advances in understanding variable expression and …

… The reduced SLCO1B1 expression likely results in less OATP1B1-mediated … encoding
OATP1B1 (that alter sulfonylurea transport into the liver) and CYP2C9 (that alter metabolism of …

… poor substrate of OATP2B1 and that the absolute hepatic expression of OATP2B1 is
approximately one-third of the more efficient CPI transporter, OATP1B1 (Badee et al., 2015). …

… OATP2B1, initially referred to as OATP-B, was originally cloned from human … OATP family,
along with OATP1B1 and OATP1B3. In contrast to the liver-specific expression of OATP1B1 …

… organic anion transporting polypeptide family (OATP, SLC21/SLCO), organic anion transporter
family (OAT, SLC22), organic … protein expression of transporter molecules in the liver and …

… associated with reduced expression of SLCO1B1 mRNA in the liver and worse glycemic …
the organic anion-transporting polypeptide, OATP1B1, which facilitates the hepatic uptake of …