Structure of the human secretin receptor coupled to an engineered heterotrimeric G protein

S Fukuhara, K Kobayashi, T Kusakizako, W Iida… - Biochemical and …, 2020 - Elsevier
Secretin is a gastrointestinal hormone that exerts multiple physiological functions via … of
the secretin receptor (SECR). SECR belongs to the class B G-protein-coupled receptors and is …

Secretin activates brown fat and induces satiation

S Laurila, L Sun, M Lahesmaa, K Schnabl… - Nature …, 2021 - nature.com
… In 2018, we reported that the gut hormone secretin mediates meal-… that secretin receptors
(SCTR) were abundantly expressed in murine BAT 12 . Feeding increased circulating secretin

Molecular cloning, immunological characterization, and expression analysis of gonadotropin-releasing hormone (GnRH) in the brain of the Chinese alligator during …

H Nie, R Zhang, X Yu, Y Zhang, P Yan, E Li, R Wang… - Gene, 2021 - Elsevier
… In the present study, full-length cDNAs encoding GnRH1 forms, its predominant localization
within brain and peripheral tissues, and GnRH1 peptide concentrations in the hypothalamus …

[HTML][HTML] Characterization of spexin (SPX) in chickens: Molecular cloning, functional analysis, tissue expression and its involvement in appetite regulation

F Meng, Y Yu, J Li, X Han, X Du, X Cao, Q Liang… - Poultry Science, 2023 - Elsevier
… Using chicken (c-) as a model, the full-length cDNA encoding cSPX precursor was cloned,
and it was predicted to generate a mature peptide with 14 amino acids conserved across …

Molecular cloning and characterization of STC1 gene and its functional analyses in yak (Bos grunniens) cumulus granulosa cells

X Yang, J Ma, L Mo, Y Xiong, X Xiong, D Lan, W Fu… - Theriogenology, 2023 - Elsevier
… Repressing the expression of STC1 resulted in defective proliferation and survival of yak …
the expression of STC1 repressed the secretion of progesterone and promoted the secretion of …

… cloning of crustacean hyperglycemic hormone (CHH) family members (CHH, molt-inhibiting hormone and mandibular organ-inhibiting hormone) and their expression …

JS Chung, A Christie, E Flynn - General and Comparative Endocrinology, 2020 - Elsevier
Molecular cloning of four cDNAs encoding prepro-crustacean hyperglycemic hormone (CHH…
encoded CHH isoforms and two putative post-translationally derived CHH variants …

Identification, characterization, and expression analysis of a serotonin receptor involved in the reproductive process of the Pacific abalone, Haliotis discus hannai

MR Sharker, ZP Sukhan, SC Kim, WK Lee… - Molecular biology …, 2020 - Springer
… A cDNA encoding the 5-HT type 1 receptor was identified from the tropical abalone, H. asinina
[16]. It was highly homologous to the Aplysia 5-HT 1 and the six transmembrane domains, …

Cholecystokinin 1 and 2 in red seabream Pagrus major: molecular cloning, response to feeding, and a potential indicator of dietary protein source quality

TTM Huong, K Murashita, A Senzui, T Matsumoto… - Fisheries science, 2020 - Springer
… sequence encoding cck for red seabream has not yet been deposited in the GenBank
database, we firstly cloned the complementary DNA (cDNA) to enable the following expression

Mechanism of receptor assembly via the pleiotropic adipokine Leptin

A Tsirigotaki, A Dansercoer… - … & Molecular Biology, 2023 - nature.com
… in vitro, we sought to investigate receptor assembly in the plasma membrane of living cells.
To this end, we conducted triple-color single-molecule imaging by total internal reflection …

Blood coagulation factor X: molecular biology, inherited disease, and engineered therapeutics

RM Camire - Journal of thrombosis and thrombolysis, 2021 - Springer
… In this brief review, I will summarize key developments in the molecular characterization of
FX, discuss the molecular basis of FX deficiency, highlight difficulties in expressing rFX, and …